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The Immune System – Multimedia

App Note / Case Study

Using the µEncapsulator 1 to Capture Single Cells in Droplets with Beads

In order to simplify high throughput single cell methods, Dolomite has developed the µEncapsulator 1 System, a compact module that simply and securely holds a droplet generating chip, convenient sample reservoirs, and an output reservoir
Comparison of Normal and Asthmatic Bronchial Epithelial Cells and Smooth Muscle Cells in Monolayer and RAFT™ 3D Cell Culture System content piece image
Poster

Comparison of Normal and Asthmatic Bronchial Epithelial Cells and Smooth Muscle Cells in Monolayer and RAFT™ 3D Cell Culture System

The RAFT™ 3D cell culture system provides a valuable tool to investigate different cell types singularly or in co-cultures in an in-vivo like collagen based microenvironment.
Mobility of Aeroallergens in Home: Effect of Location of Air Sampling and Implication for Evaluation of Patient Exposure content piece image
Poster

Mobility of Aeroallergens in Home: Effect of Location of Air Sampling and Implication for Evaluation of Patient Exposure

The Inspirotec sampler permitted the easy testing of multiple locations within a household. Air sampling simultaneously at 12 locations by other technologies would have been technically challenging. These were run by an untrained operator.
App Note / Case Study

ENRICHMENT AND PURIFICATION OF CD3+ T-CELLS FROM HUMAN UMBILICAL CORD BLOOD

Quad Technologies’ has partnered with the University of Massachusetts Medical School (Worcester, MA, USA) to evaluate the performance of the MagCloudz™ Streptavidin cell separation kit.
Contract Assay Services at STEMCELL Technologies Inc. content piece image
Video

Contract Assay Services at STEMCELL Technologies Inc.

App Note / Case Study

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies

The rapid growth of the therapeutic antibody market has increased the interest in modeling of the antibody structure and in understanding the factors that affect the function and the stability of antibodies.
Metabolomic profile of multiple sclerosis patients by means of 1H-NMR analysis content piece image
Poster

Metabolomic profile of multiple sclerosis patients by means of 1H-NMR analysis

Multiple sclerosis (MS) is a chronic disease characterized by a high level of heterogeneity. Metabolomics is an “-omics” approach with the potential to discover new biomarkers.
Lab-on-DVD: A Novel Platform for Point of Care Diagnostics content piece image
Video

Lab-on-DVD: A Novel Platform for Point of Care Diagnostics

We report on the development of a modified commercial DVD reader with all the necessary components required for a truly integrated lab-on-a-chip system, with the capability to deliver high-resolution images down to 1 μm in size.
Monitoring Dynamic Interactions of Tumor Cells with Tissue and Immune Cells in a Lab-on-a-Chip content piece image
Video

Monitoring Dynamic Interactions of Tumor Cells with Tissue and Immune Cells in a Lab-on-a-Chip

A complementary cell analysis method has been developed to assess the dynamic interactions of tumor cells with resident tissue and immune cells using optical light scattering and impedance spectroscopy to shed light on tumor cell behavior.
Reporter Bioassays to Assess Therapeutic Antibodies for Immunotherapy Programs content piece image
Poster

Reporter Bioassays to Assess Therapeutic Antibodies for Immunotherapy Programs

Immunotherapy, also called biologic therapy or biotherapy, stimulates certain parts of the immune system to fight diseases such as cancer. Important drug targets in immunotherapy include: Co-inhibitory receptors, such as PD-1/PD-L1, CTLA-4, LAG3, Tim3; and co-stimulatory receptors, such as GITR, CD40, OX40, 4-1BB.
Current approaches to assaying these targets are cumbersome and variable. Here we offer an improved in vitro bioassay approach.
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