Therapeutic Delivery – Webinars and Online Events

In this webinar, you’ll gain insights from experts in CGT development who will explore their experiences of CQA assays, sharing advice on how to overcome the challenges you may face in your CGT journey.

To ensure the safety and efficacy of LNP-based drugs, comprehensive characterization of these sophisticated molecules–the lipids and the genetic cargo–is paramount.

This webinar highlights the latest affinity chromatography solutions for the quick and easy purification of multiple AAV serotypes across a variety of column setups.

In recent years we’ve seen a steep rise in the application of nanomedicine, particularly with the use of viral and non-viral delivery vectors for nucleic acids, for use in vaccine development and cell and gene therapy.

Detailed and sensitive characterization of ionizable lipids that make up lipid nanoparticles (LNP) and their related impurities is necessary to ensure the quality of mRNA therapies. Additionally, there are mRNA quality attributes such as 5’ capping that directly impact efficacy and safety.

The Problem
LNPs are a valuable tool in the repertoire of gene and vaccine delivery vectors but LNP development is a complex multi-step process.

Speaking at the Advances in Drug Discovery & Development 2022 online symposium, Adam Crowe from SCIEX discussed how an ionizable lipid was analyzed with liquid chromatography coupled with mass spectrometry.

During this webinar, you will understand how capillary electrophoresis (CE) and LC-MS are being used to ensure vaccine and cell and gene therapy product quality. We will discuss how LC-MS is being used to identify impurities present in lipid nanoparticle (LNP) vaccines that have been found to deactivate mRNA. We will also cover how CE is being used in viral vector production to ensure product quality.

Now in its second year, this online symposium will provide those working within academia and pharmaceutical development the opportunity to hear from experts within the field. Focus will be given to the latest advances in small molecule drug discovery and development, biopharma and biotechnology

Accessed via mobile, tablet or PC, this inaugural free-to-attend event will provide those working within academia and pharmaceutical development the opportunity to hear from experts within the field. Focus will be given to the latest advances in small molecule drug discovery and development, biopharma and biotechnology.