Advancing mRNA Therapeutics With Mass Photometry

The impurities that arise during the manufacture, purification, and storage of mRNA therapeutics threaten the efficacy, stability, and safety of these drugs. The highly polar, single-stranded nature of these molecules results in unwanted sample heterogeneity, consisting of double-stranded RNA, mRNA fragments, and mRNA multimers. This webinar explores the limitations of traditional analytical methods for characterizing large mRNA transcripts and how mass photometry can generate reliable data quickly and in native conditions. Watch this webinar to discover: The critical quality attributes of mRNA therapeutics How impurities arise and why this threatens drug efficacy The role of mass photometry in mRNA characterization