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Christin Radon smiling next to the title of her presentation

SPR 101: From Binding Events to Confident Decisions

Video  
Laura Hemmingham, PhD
 speaking with 
Christin Radon, PhD

Surface plasmon resonance (SPR) goes beyond measuring binding affinity—it reveals how molecules interact in real time, helping researchers make more confident decisions throughout drug discovery.

In this episode of Teach Me in 10, Dr. Christin Radon, a Biacore and Reagents Application Specialist at Cytiva, explains the fundamentals of SPR and why binding kinetics are often the missing piece behind functional outcomes. She also walks through how SPR works at the sensor surface, how modern systems support guided workflows, and how researchers can generate reliable kinetic data from both purified and complex samples.

From association and dissociation rates to interaction stability and lifetime, discover how SPR delivers deeper insight into biomolecular interactions without the need for labels.


Watch this episode to explore: 

  • How SPR measures real-time, label-free biomolecular interactions
  • Why binding kinetics and interaction stability matter beyond affinity alone
  • Practical tips for reducing nonspecific binding and optimizing SPR experiment


Further resources: