We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Targeting Tumors: Challenges of Antibody-Drug Conjugates

Video   Jun 12, 2018 | Nature Video, YouTube

 

Treating cancer requires aggressive but targeted therapy. Some cancer drugs are too toxic because they damage healthy cells as well as tumor cells. So researchers are trying to develop ways to make sure drugs only target the right cells.

One solution is to attach drugs to antibodies specific to a protein expressed on tumor cells. These drugs are called antibody-drug conjugates (ADCs).

More than two dozen ADCs are currently being used in the clinic to treat diseases like Hodgkin's lymphoma and breast cancer, and researchers are developing many more. But it's taken decades to find the right combination of drug, antibody target and linker, and then make sure the right amount of ADC hits the tumor. 


 
More Information
 
 
 

Recommended Videos

How Does Chemotherapy Work?

Video

Discover how chemotherapy drugs use cytotoxic agents to attack cancer cells and the impact they have on your body.

WATCH NOW

Organoids for Drug Discovery

Video

Dr Bahar Ramezanpour, VP Business Development, Hubrecht Organoid Technology, explains the advantages of using organoids over traditional cell culture systems and how they are used to develop therapeutics.

WATCH NOW

A New Way To Detect More Cancers Earlier

Video

Dr Anne Marie Lennon of Johns Hopkins University School of Medicine in Baltimore, Maryland, describes a new way to detect eight common types of cancer (esophagus, stomach, colon, pancreas, liver, breast, lung, and ovarian) using a simple blood test. The technique combines genetic indicators with blood protein markers to identify these cancers earlier than ever before, while avoiding false positives.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Cancer Research Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE