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Accelerating Cell Line Development From Transfection to Manufacturing

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Generating a highly expressing, regulatory compliant clonal cell line is key when developing a biopharmaceutical. Yet cell line development is labor-intensive, time consuming and costly.

The production of a high-quality and productive cell line requires both an expression system that yields high expressing clones and a workflow that allows selection of the highest producing clones.

In this webinar, you’ll discover how combining a single-cell analysis platform with a novel glutamine synthetase-Chinese hamster ovary expression system can yield highly productive, scalable, clonal cell lines for developing biopharmaceuticals.

Attend this webinar to:

Hear about the workflow and techniques required to build a panel of scalable clones
Learn about picodroplets and their advantages for cell line development
Discover how real-world researchers drastically reduced their workflow timeline and costs
Learn how automation can enable you to achieve regulatory accepted cells without compromising on monoclonality, traceability, productivity or scalability

Speaker

Dr. Jonathan H. Dempsey

Chief Scientific Officer

Pathway Biopharma

Jonathan is the Managing Director of Pathway Biopharma Ltd, a company setup to support the commercialisation of new technologies and biomedicines. Pathway Biopharma was founded to act as the guide for companies who have a great therapy or idea, but who may not know how to get to the point where they can begin to develop that idea. Jonathan is expert in the discovery and development of biopharmaceuticals, specifically monoclonal antibodies and in mammalian cell line development, upstream process development, and the transfer of cell-based processes to manufacturing. His career, spanning almost 30 years, has been spent working on biological molecules expressed in living organisms. Jonathan has a PhD in Industrial Biotechnology from the University of Edinburgh where he studied the impact of the manufacturing environment on cell physiology. After many years developing bioprocesses for biomedicine manufacture with leading companies such as Celltech, Lonza and Cambridge Antibody Technology, Jonathan then went on to commercialise innovative technologies with Invitrogen. He set up Pathway Biopharma to assist companies in their journey to market and now works with virtual, small, and medium size companies to support them in bridging the gap from idea to product. Jonathan also works with Universities and Investors to identify and commercialise innovative technologies applicable to this industry.

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Chief Scientific Officer

Pathway Biopharma

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