We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

Accelerating Drug Discovery and Safety Studies on SyncroPatch 384, User Perspectives

In this webinar there will be two speakers discussing:

Title:

High-Throughput Functional Evaluation of Melanocortin Compounds at the MC4R-Kir7.1 Complex: Biased Signaling at the Melanocortin 4 Receptor

Title:

CiPA Based Evaluation of Proarrhythmia 

Watch now to learn about:

  • Melanocortin 4 receptors (MC4R) are G-protein coupled receptors (GPCR)
  • Loss-of-function MC4R mutation are linked to early-onset syndromic obesity.
  • MC4R is the first GPCR reported to functionally directly interact with the inward rectifier potassium channel Kir7.1.
  • Evaluation of validated channel assays and applied them to several drugs with questionable proarrhythmic safety.
  • Applying the CiPA Approach to Evaluate Cardiac Proarrhythmia Risk ofsome Antimalarials Used Off-label in the First Wave of COVID-19


Speakers
Dr Ciria Hernandez, MD, Ph.D
Dr Ciria Hernandez, MD, Ph.D
Assistant Research Scientist, University of Michigan Life Sciences Institute
Yuri Kuryshev
Yuri Kuryshev
Principal Scientist, Charles River Laboratories
Advertisement