Enhancing Gene Therapy With Precise AAV Capsid Analysis
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Adeno-associated viruses (AAV) are a common vector for gene therapies and consist of a genome payload inside a capsid shell. During production, empty capsids may be produced that lack a DNA payload, making the ratio of empty–full capsids a key quality attribute.
In this webinar, Dr. Chelsea Pratt will explore the field of gene therapy, highlighting key challenges and the predominant current techniques. She will discuss how a new kit from Bio-Rad can simultaneously measure viral titer, capsid titer and empty–full ratio in AAV samples, empowering and improving gene therapy research.
- The importance of understanding empty–full vector ratios in gene therapy development
- Common techniques in measuring empty–full AAV titer
- A new digital PCR approach to measuring empty–full titer
- How new techniques compare to previous methodologies
