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Influenza Vaccine Viral Protein Profiling for Viral Potency

Influenza Vaccine Viral Protein Profiling for Viral Potency  content piece image

Influenza vaccines typically consist of either attenuated, inactivated viruses or virosomes, which are virus-like particles that contain antigenic proteins. The viral potency is normally measured by the quantification of hemagglutinin (HA), a type of glycoprotein embedded in the viral bilayer and on the virus's outer surface contained in the virosomes.

In this on-demand webinar, we will discuss a new approach to profiling influenza proteins. The solution demonstrated will showcase how commercially available kits and prebuilt cartridges used together with capillary gel electrophoresis with sodium dodecyl sulphate (CE-SDS) can separate viral proteins with ease.

  Watch this webinar to:

  • Understand how CE provides highly resolved separation and detection of individual HA proteins
  • Discover how CE-SDS provides a fast reproducible assay that is compatible with 96 well plates
  • Identify how the method can be adapted to the analysis of multiple viral strains
Speakers
A picture of Stephen Lock, PhD
Stephen Lock, PhD
Biopharma EMEAI Marketing and Market Development Manager SCIEX
A picture of Patrick Buckley, PhD
Patrick Buckley, PhD
Senior Validation Specialist Seqirus