Therapeutic siRNAs: Considerations for “Picking the Best One”
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The discovery of small interfering RNAs (siRNAs) has revolutionized therapeutic development by enabling precise down-regulation of gene expression in human cells, offering significant potential to treat and potentially eradicate diseases.
Selecting optimal siRNAs for drug discovery and clinical development requires careful consideration early in the process.
This webinar delves into some key factors for selecting effective therapeutic siRNAs.
You’ll learn about integrating intellectual property and manufacturing with sequence selection and molecular design, leveraging machine learning for mRNA target selection and utilizing medicinal chemistry as a "toolbox" for siRNA lead optimization.
- Explore some key factors in siRNA selection and design
- Learn about machine learning applications in siRNA development
- Discover how applying medicinal chemistry can be applied in siRNA lead optimization
