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Quantify and Characterize Host Cell Protein With Confidence

Quantify and Characterize Host Cell Protein With Confidence content piece image

Harnessing the power of biological systems to synthesize proteins has enabled the production of numerous life-changing biopharmaceuticals. Chinese hamster ovary (CHO) cells are widely used to produce recombinant proteins via cell culture, but this approach has a major caveat: these host cells also produce various proteins to support normal cell growth, survival and proliferation. These host cell proteins (HCPs) pose a risk for immunogenicity of biotherapeutic products and must be reduced to sufficiently low levels to ensure safety and efficacy.

Download this whitepaper to learn more about how:

  • Dilutional linearity enhances reliability
  • Undetected HCP can be minimized
  • Consistently low variation ensures reproducible data