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How Carcinogens Trigger Development of Breast Cancer
News

Scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger cancer.

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Converting Autoimmunity Drugs Into Powerful Anticancer Treatments
News

A team from the University of Southampton has discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular “switch”.

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Cell Culture Systems for Anticancer Drug Screening
News

A newly published paper provides an insight into in vitro based testing of anticancer drugs.

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Olaparib Approved as First Gene-targeted Medicine for Prostate Cancer
News

Olaparib is a precision medicine that works by selectively targeting and killing cancer cells with faulty DNA repair machinery. On May 19, 2020, the Food and Drug Administration (FDA) approved olaparib for adult patients with a specific type of prostate cancer .

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Targeting Non-cancer Cells To Reduce Liver Tumor Growth
News

A treatment that uses small molecule drugs to target “senescent” cells known as "senotherapy" has been shown to blunt liver tumor progression in animal models.

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Nanobowls Aid Delivery of Chemotherapy Drugs to Cancer Cells
News

Researchers have designed nanobowl-supported liposomes that improve the loading and delivery of cancer drugs.

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Organoids: Exploring Liver Cancer Initiation and the Possibilities of Personalized Glioblastoma Treatment

Article

In this article, we explore the various types of organoids under development and shine a spotlight on some of the different approaches to organoids in cancer research.

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The Coronavirus Outbreak
Article

On December 31, 2019, the first cases of a novel coronavirus were identified in Wuhan City, Hubei Province, China. Here, we curate a collection of news and content related to the outbreak.

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Exploring Differences in Drug Response With Dr Namandje N. Bumpus
Article

For the same dose of the same drug, two individuals might experience very different effects. This variation in drug response can be impacted by several drug-specific, genetic, biological, and environmental factors, and the interplay between these factors. In this interview, Namandje N. Bumpus, Ph.D, Associate Dean for Basic Research and Associate Professor of Medicine, from Johns Hopkins, elaborates on her work exploring the differences between people in relation to drug response.

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Cell Communication and Signaling Dysregulation in Cancer
Article

Here, Caroline Hill, Ph.D., from The Francis Crick Institute, UK, shares insight into cell communication and signaling dysregulation – her area of expertise. Her research group are focused on understanding the signals sent to, and sent by cells – and how this communication influences cellular behavior. As well as touching on her research, Caroline discusses the evolution of cancer and suggests strategies for encouraging more women to pursue a career in STEM.

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