High-Throughput Protein Quantitation for Process Optimization
Scientists at Pall Life Science assessed the relative merits of Protein A HPLC and Protein A biolayer interferometry (BLI) to determine concentrations of monoclonal antibodies (mAb) in a complex feedstock. The results illustrated that the Octet® BLI system provides a fast, accurate and economical means of quantifying mAbs, and decreases process development efforts.
Targeting Cancer Through Induced Viral Mimicry
Researchers from Sanford Burnham Prebys have been awarded two grants from the National Institutes of Health to study an emerging therapeutic strategy known as viral mimicry. Dr. Charles Spruck and colleagues are working to understand how a specific pathway silences endogenous retroviruses and retrotransposons selectively in breast cancer cells and whether this could expose a vulnerability that could be exploited.
Cancer Research Horizons: Driving Innovation and Strengthening Academia–Industry Collaboration
In April 2022, Cancer Research UK unveiled Cancer Research Horizons, its new approach to driving innovation in the field. Technology Networks had the opportunity to speak with two members of Cancer Research Horizon’s executive leadership team to learn more about some of the cutting-edge experimental capabilities that will be used to interrogate cancer biology more thoroughly.
Imaging Approach Helps To Detect Lung Cancer Earlier
Researchers have discovered a way to identify lung cancer at the cellular level in real-time during a biopsy procedure.
Multiple Myeloma Test Detects More Deadly Forms of the Disease
Investigators say that a standard test for the common blood cancer multiple myeloma also holds clear clues that the patient has one of the most uncommon and deadly forms of this cancer, IgD multiple myeloma.
Stem Cell Therapy Engineered To Treat Aggressive Brain Cancer
Investigators at Brigham and Women’s Hospital and Harvard Medical School have devised a novel therapeutic method using stem cells taken from healthy donors to treat glioblastomas post-surgery by attacking glioblastoma-specific tumor cells.
Epilepsy Drug Halts Growth of Tumors by Suppressing Neurons in Mouse Model
People with neurofibromatosis type 1 have hyperexcitable neurons which leads to tumors developing. Researchers have identified that an epilepsy drug can suppress this hyperactivity and halt tumor growth.
Re-Educating the Immune Response To Treat Type 1 Diabetes
CAR T-cell therapy is largely used to treat cancers, but here we explore how Dr. Leonardo Ferreira and his team are using CAR T-cell therapy to treat Type 1 diabetes.
In Vitro Diagnostics Needs Seismic Change To Improve Patient Outcomes and Deliver Economic Benefits
In this opinion piece, Andrew Goutler discusses the current state of in vitro diagnostics and how it is time to seize the potential of emerging techniques and technologies to deliver improvements across this vital area of clinical testing.
Eight Ways To Make Your Lab More Sustainable
Download this guide to discover tips on avoiding single-use plastics, managing your cold storage and conserving water and energy.
Nine Ways To Improve Your Data Reproducibility
Download this guide to discover tips on improving your data reproducibility such as checking guidelines specific to your field, maintaining equipment and understanding analysis software.
Tried and True ‒ German-Engineered Cell Strainers are Bringing Research Further
Publishable results in cell-based research are only as reliable as their preparation. Something as small as the cell strainer used in an experiment can make a difference in the quality and success of results and their credibility for publication.
Recent Developments in Proteomics Research
Here, we take a closer look at some recent developments in the world of proteomics research.