Using Cell-free DNA as a Marker for Liver Cancer Diagnosis

Blog

During this year’s AACR conference we spoke to Kang Zhang, M.D., Ph.D. from the University of California, San Diego about the collaborative work he has been doing with the Laboratory for Advanced Medicine. He discusses their recent study findings on the use of a blood-based method to look at cell-free DNA as a marker for liver cancer diagnosis and prognosis.

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The Glycome and Cancer

Article

The surfaces of cancer cells frequently express different types of glycoproteins, and because healthy cells don’t express these molecules (or do so at a much lower level), there has been significant interest in them as potential anticancer targets. Recent advances suggest we are about to see a resurgence in cancer glycomics.

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New Subtype of Prostate Cancer

New Subtype of Prostate Cancer

News

Researchers led by the University of Michigan Rogel Cancer Center have identified a new subtype of prostate cancer that occurs in about 7 percent of patients with advanced disease.

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Targeting the Engine Room of the Cancer Cell
News

Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.

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Cryo-EM Reveals Interaction Between Major Drug Targets
News

For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer.

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New Ovarian Cancer Target
News

Researchers have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer. This new study opens a potential avenue for treating ovarian cancer. Since Calcitriol is an FDA-approved drug, no additional research is needed before the drug can advance to human clinical trials for ovarian cancer.

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Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells

Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells

Article

Although cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.

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Cell Potency: Totipotent vs Pluripotent vs Multipotent Stem Cells
Article

Here we discuss the differences between totipotent, pluripotent, and multipotent stem cells.

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Henrietta Lacks: The Mother of Modern Medicine
Article

A portrait of Henrietta Lacks has recently been unveiled at the Smithsonian’s National Portrait Gallery, to recognize her life and the vital contributions HeLa cells have made to science.

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How Mass Spectrometry Has Changed the Cancer Diagnostics Game
Article

Although histopathology is still the gold standard for diagnosing cancer, molecular analysis using MS has gained traction in recent years for detecting tumors, monitoring progression, and even predicting treatment response.

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