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Fighting Cancer on Two Fronts

Video

Nia Clements is a cancer researcher who has found a potential treatment to multiple forms of cancer. What's more, is she did all of this before even graduating high school.

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How To Prevent Cell Culture Contamination

Infographic

Cells in culture are vulnerable to contaminants derived from a large range of potential sources. Download this infographic to arm yourself with knowledge about different types of contaminants, and find out how to avoid contamination of your cultures.

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The Promise and Limits of Cancer Immunotherapy

Video

A pioneer in cancer care treatment, oncologist Lennie Sender has a deep understanding of both the possibilities and limitations of harnessing the immune system to treat different types of cancer.

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Shining a Light on Rare Nerve Tumors

News

When a protein named "Merlin" fails to do its job, people can develop slow-growing, life-disrupting auditory nerve tumors that can disrupt their hearing and balance. Now scientists at Cincinnati Children's have discovered much more about how Merlin does its job – by working behind the scenes through a network of more than 50 other proteins.

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Scientists Crack the Chemical Code of Complex “Anti-tumor Antibiotic”
News

After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex "anti-tumor antibiotic" known to be highly effective against cancer cells as well as drug-resistant bacteria, and have reproduced it synthetically in the lab for the first time.

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Targeted Therapy Proves Effective Against Aggressive Blood Cancer in Clinical Trial
News

A multi-institutional clinical trial has given good results for a targeted therapy to treat a rare, aggressive blood cancer known as blastic plasmacytoid dendritic-cell neoplasm (BPDCN).

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Exposing and Exploiting Cancer’s Metabolic Addictions
News

Where a tumor arises dictates specific metabolic vulnerabilities, identifying potential targets for effective cancer treatments.

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The Evolving Field of Cancer Biomarkers

Article

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

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Sensitivity vs Specificity
Article

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

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Preclinical Modeling of Tumor Metastasis and Resistance: Current Challenges and New Approaches
Article

To improve cancer survival rates, pharma and biotech researchers must develop safe and effective therapies to treat not only primary tumors, but also metastatic growths and tumors that have acquired resistance.

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The Power of Proteogenomics in Precision Medicine
Article

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.

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