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Ready for a change of scenery?

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Get a new perspective on your sample QC with the Agilent 4150 TapeStation system and open up new horizons. Ideal for handling smaller numbers of samples, the system with ScreenTape assays delivers fast, reliable results within any NGS workflow.

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Single-Cell DNA Sequencing Weaves a Way Towards Personalized Cancer Treatment

Article

High-throughput single-cell analysis has been regularly acclaimed as a transformative technology for sequencing and a huge step towards the goal of personalized medicine. Will Tapestri, a sequencing platform developed by Mission Bio, be the game-changer in DNA analysis we have been waiting for?

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8 Characters You’ll Find in Every Lab

Infographic

In this poster we highlight eight characters you will find in every lab. Which character are you most like?

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Maturation Process of Natural Killer Cells Mapped
Maturation Process of Natural Killer Cells Mapped
News

Notch signaling is necessary for the normal development and function of natural killer cells. This could be significant for the natural killer cells’ ability to fight cancer and infections.

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Drug Seeks Out Receptors in Sarcoma Cells, Shrinks Tumors
Drug Seeks Out Receptors in Sarcoma Cells, Shrinks Tumors
News

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.

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Tumor Cells Invade & Conquer – But How?
Tumor Cells Invade & Conquer – But How?
News

Researchers from the Institut Pasteur and the Champalimaud Centre for the Unknown, have just discovered a new mechanism that may explain how tumoural cells can eliminate their neighbours and spread throughout the body.

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Loss of Tight Junction Protein Promotes Development of Precancerous Cells
Loss of Tight Junction Protein Promotes Development of Precancerous Cells
News

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.

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Excess Body Weight Responsible for 4% of Cancers Worldwide
Excess Body Weight Responsible for 4% of Cancers Worldwide
News

Policies, economic systems, and marketing practices that promote the consumption of energy-dense, nutrient-poor food, changing behavioral patterns that couple high total energy intake with insufficient physical activity, and human-built environments that amplify these factors are driving a worldwide rise in excess body weight, according to a new report.

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Drug Cocktail Cripples Cancer Cells
Drug Cocktail Cripples Cancer Cells
News

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

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Chemists Design Novel One-Pot Reactions to Access Complex Natural Product Analogs for Drug Discovery
Chemists Design Novel One-Pot Reactions to Access Complex Natural Product Analogs for Drug Discovery
Article

Scientists have discovered powerful new reactions for the synthesis of nature-inspired privileged structures – one-pot, modular, elegantly designed chemical reactions that could minimize the gap between the chemical and biological space. Their study findings could be a turning point for the discovery of unmet diseases.

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Emerging Classes of Next-generation Biotherapeutics
Emerging Classes of Next-generation Biotherapeutics
Article

We are entering uncharted territory in biopharmaceutical development. Emerging new classes of treatments are harnessing the natural power of viruses and cells and engineering them to fight human diseases. As our arsenal of conventional therapies begins to fail, a new army of biotherapeutics is on the horizon. Here, we look at two new classes of treatments leading the charge.

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High-Throughput LC-MS for Early Drug Screening and Biomarker Detection
High-Throughput LC-MS for Early Drug Screening and Biomarker Detection
Article

In this article, we explore two novel high-throughput analytical methods based on liquid chromatography-mass spectrometry (LC-MS) analysis that can augment early drug screening and biomarker detection in the clinic.

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Medical Devices: How to Master New Clinical Evaluation Report Criteria
Medical Devices: How to Master New Clinical Evaluation Report Criteria
Article

To achieve regulatory compliance and authorization for sale in Europe, every medical device must be supported by a Clinical Evaluation Report which documents the entire clinical evaluation process. Read on for recommendations on how manufacturers can keep up with the changing regulation landscape.

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Exploiting Epigenetics in Cancer Treatment
Exploiting Epigenetics in Cancer Treatment
Article

Changes to the complex of DNA and the proteins that form chromatin are important drivers in many cancers. We explore the challenges and progress in the development of new therapies targeting epigenetic regulators.

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Through the Looking Glass of Single Cell Proteomics
Through the Looking Glass of Single Cell Proteomics
Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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