Cancer is an extremely complex group of diseases. As it progresses, tumors can evolve to comprise varied cell types with distinct morphological and genetic features. This diversity – or heterogeneity – is reflected at many levels. In this infographic, we explore the mechanisms causing intratumor heterogeneity and the clinical implications of cancer heterogeneity.
Simulator Technology Can Predict Optimal Vaccine Dosing
Certara is developing biosimulation and tech-enabled approaches to help scientists answer key questions at various stages of the development pipeline, serving to inform and accelerate the path to regulatory approval. One such approach, the company’s Vaccine Simulator™, can be leveraged across different therapeutic areas to determine optimal vaccine dosing and dosing regimens for different patient cohorts.
Memories of Cancer: What the Extracellular Matrix Can Tell Us About Cancer and How To Combat It
Chronic inflammation has long been linked to cancer, especially the most lethal and untreatable types. But the details of this mysterious relationship have also long defied scientific elucidation – until now.
Discovering New Targets for Cancer Vaccines
Research conducted by a team from MIT, suggests that vaccinating against certain proteins found on cancer cells could help to enhance the T cell response to cancer cells.
Moffitt Joins National Pilot Project To Increase Diversity in Cancer Trials
Moffitt Cancer Center is joining a national pilot project being conducted by the American Society of Clinical Oncology and the Association of Community Cancer Centers. The project is testing a research site self-assessment tool and an implicit bias training program designed to increase racial and ethnic diversity among individuals with cancer participating in clinical trials.
Improvements in Optical Tissue Clearing Help Clinicians To Diagnose Cancer
The ability to visualize cancerous tumors and metastatic tissue in three dimensions helps clinicians diagnose the precise type and stage of cancer. Now researchers have developed specialized hydrogels designed to rapidly remove fats from tissues, which are a factor in tissue opacification.
Fruit Fly Research Is Helping To Discover New Anticancer Strategies
The experience of a fruit fly dying from cancer may seem worlds away from that of a human with a life-threatening tumor, yet researchers are discovering commonalities between the two that could reveal ways to improve the survival of cancer patients.
Scientific Storytelling: It's All About Context
In this interview, Dr. Yotam Ophir discusses the different types of narratives that exist around science, their impact and why retractions should be interpreted as a positive step in scientific progress.
An Introduction to the Light Microscope, Light Microscopy Techniques and Applications
Today, light microscopy is a core technique in many areas of science and technology. In this article, we explore the basic working principle of light microscopy and discuss some more advanced forms of light microscopy that are commonly used today, comparing their strengths and weaknesses for different applications.
All Cancers May Fall Into One of Two Classes
Technology Networks spoke with Dr. Rod Bremner to find out more about a cancer classification technique and the possible implications for future cancer treatments.
Improved Characterization of Antibody-Drug Conjugates
In a new research study published in Analytical Chemistry, scientists showcase a novel mass spectrometry-based method that enables high-throughput characterization of ADCs. Technology Networks spoke to Eli J. Larson, lead author of the paper, to learn more about the method and some of the benefits it offers over existing analytical techniques.
Flow Cytometry Capabilities Guide
Flow cytometry enables the simultaneous analysis of multiple proteins, gene expression, and cell functions from an individual cell. This technology makes it possible to obtain a statistically relevant amount of data.
Best Practices for Returning to the Lab
Download this free how to guide to learn more about the tips and best practices for returning to the lab after an unexpected shutdown.
Fundamentals of Therapeutic Drug Monitoring: Definition, Importance and Methods
Download this listicle to discover answers to key questions such as: can therapeutic drug monitoring (TDM) be used for all drugs? Which drugs are currently monitored using TDM approaches? What analytical methods are used for TDM?
Data Integrity in Research: What Does It Mean and How Do We Achieve It?
Download this listicle to learn about the importance of data integrity in research, data integrity in the digital age and improving data integrity.