Imagine A New Way Forward in Spatial Biology & Cancer Research
Bringing together the needs of spatial biology with the advanced detection capabilities of mass spectrometry. It’s time to simultaneously observe how drugs affect both protein and metabolic states from the same tissue section, with no limit on proteins of interest.
Neurotrophic Factors (NTFs) for Neural Cell Culture
Neurotrophic factors (NTFs) control nerve cell proliferation and differentiation. The ability of these factors to promote cell survival and regeneration following injury, especially after stroke and brain injury, is applied in nerve cell culture and differentiation research. They are the first factors tested in the Central Nervous System (CNS) as therapeutic biologics.
The PhenoImager™ HT (formerly Vectra ® Polaris™) is the premier and most highly cited digital pathology imager for spatial phenotyping. Featuring whole-slide multispectral scanning, this system can be easily integrated into high-throughput workflows that need to accommodate for scalability.
Xenium In Situ
Ductal carcinoma in situ (DCIS), cancer cell growth that starts in the milk ducts, is the most common form of breast cancer. However, why some DCIS progress to invasive carcinoma but others remain innocuous is still unclear. In a recent study, three groundbreaking technologies—Chromium Single Cell, Visium Spatial, and Xenium In Situ—were used to achieve a deeper understanding into the biology of a single, breast cancer patient-derived, FFPE tissue block.
Ketogenic Diet May Mitigate Low Platelet Counts From Chemotherapy, Suggests Mouse Study
A ketogenic diet may mitigate reduced blood platelet counts as a result of chemotherapy, according to a new study.
Exploring the Evolution and Vulnerabilities of Brain Cancer Cells
Researchers have explored how cancer cells evolve from healthy brain cells and evade treatment, which could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers.
Ultrafine Carbon Particles Accelerate Lung Cancer Development
Ultrafine particles in smoke can alter the function of immune cells in the lungs, reducing the immune response against tumors and enabling lung cancer to grow undetected.
Data Reporting, Integrity and Compliance
In this article, we examine how analytical scientists can enhance their data sharing and reporting practices, leading to improvements in data integrity and an easier route to compliance within a regulated good manufacturing practice (GMP) environment.
International Day of LGBTQIA+ People in STEM 2022
This article contains segments from five interviews with individuals currently working in STEM who identify as LGBTQIA+ to find out about their experiences, opinions and ideas to inspire the next generation.
Should #SciTwitter Migrate Elsewhere?
From tweets to toots – the online community #SciTwitter is considering a move from Twitter to an alternative online platform. In this article, we explore how Twitter has supported science communication and outreach over recent years, the motivations for migration and ask: where are you heading, #SciTwitter?
How To Build an Effective Protein Degrader
This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.
Connecting Laboratories With Data-Driven Automation Software
Download this guide to learn more about automated software and the latest solutions available.
How To Transfer From Animal-Derived Matrices to GrowDex 3D Cell Culture Matrix
Animal-derived matrices for 3D cell culture are often poorly defined and suffer from lot-to-lot variability which ultimately affects the reproducibility of the experiment – an essential element for reliable research studies.
Five Intelligent Ways To Accelerate Cell Line Development
Download this free listicle to learn more about how to use automation to optimize your cell line development workflow.
Clinical Applications of Cell Therapy
Download this listicle to explore cell therapy applications including oncology, neurodegenerative disease and diabetes.