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Latest Application Notes
Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma
Application Note

Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma

Download this app note to discover how to distinguish tumor versus normal cells in a heterogeneous sample, reconstruct cell type–specific gene regulatory network
and confirm PAX5 as a critical regulator specific to tumor B cells.
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Application Note

Imaging Organoids With Light-Sheet Fluorescence Microscopy

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Application Note

Accurate Quantification of Interferon Gamma Across Immunoassay Platforms

Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
Spatially Resolved Heterogeneity of Triple Negative Breast Cancer
Application Note

Spatially Resolved Heterogeneity of Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is unresponsive to traditional hormone or targeted therapies and highly heterogeneous. Improved understanding of the biological underpinnings and cell-type composition of TNBC is critical to developing novel targeted treatment options.
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis
Application Note

Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis

Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
Identifying an Intronic Positive Variant
Application Note

Identifying an Intronic Positive Variant

It can take approximately seven years to diagnose a patient with a rare disease. With NEW CentoXome®, this doesn’t have to be the case.
Monitoring Moisture in the Cosmetics Industry
Application Note

Monitoring Moisture in the Cosmetics Industry

Moisture content determination is a vital measurement in the production and processing of most materials. Download this app note to discover how moisture testing can eliminate production issues, help you meet legal requirements and much more.
Adjuvants for Immunotherapy and Vaccine Development
Application Note

Adjuvants for Immunotherapy and Vaccine Development

Download this flyer to discover various monophosphoryl lipid A (MPLA) adjuvants as well as a trehalose dibehenate and DDA adjuvant system for tuberculosis vaccines.
Analysis of Common Preservatives in Personal Care Products by HPLC With UV Detection
Application Note

Analysis of Common Preservatives in Personal Care Products by HPLC With UV Detection

Parabens refer to a group of p-hydroxybenzoic acid esters that are widely used as antimicrobial preservatives in many everyday products due to their broad spectrum of activity as well as their chemical and thermal stability.
Analysis of Genotoxic Nitrosamines in Losartan
Application Note

Analysis of Genotoxic Nitrosamines in Losartan

Download this app note to discover a system that demonstrates good chromatographic separation of nitrosamine compounds and provides enhanced sensitivity.
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