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Latest App Notes & Case Studies

3D rendering of glowing T cells with light rays on a dark blue background, highlighting their detailed surface structure
App Note / Case Study

Active-Release Beads for Faster, Reliable CAR T Cell Therapy Development

This application note highlights the features of active-release beads compared to the established passive-release beads for the isolation, activation, cell expansion and desired early memory cell phenotype.
Picus® 2 Sustainability Fact Sheet
App Note / Case Study

Picus® 2 Sustainability Fact Sheet

Sartorius Picus® 2 electronic pipettes are the ideal tools to accompany you in daily, repetitive liquid handling in laboratories, where the accuracy of your results, speed and ergonomics are important.
Compound Profiling Services
App Note / Case Study

Compound Profiling Services

SignalChem Biotech, now part of Sino Biological, boasts one of the largest selections of active enzymes. Leveraging this extensive collection, we offer compound selectivity profiling services to determine the inhibitory profiles and mechanisms of action of drug candidates.
SignalChem Biotech Kinases
App Note / Case Study

SignalChem Biotech Kinases

Kinases are a family of enzymes crucial in cell signaling, phosphorylating substrates to regulate various biological processes. Deregulation of kinases can lead to diseases like cancer and cardiovascular disease.
Recombinant Active Enzymes
App Note / Case Study

Recombinant Active Enzymes

SignalChem Biotech’s team of scientists specializes in crafting active signaling proteins, including kinases, phosphatases, and enzyme substrates. SignalChem Biotech Bio products are extensively used in high-throughput screenings, activity assays, binding assays, cell-based assays, protein interaction studies, and structural analyses.
Scientist Handling Testing Kit with hands in protective gloves stock photo
App Note / Case Study

Rapid Detection of Mutations Using ddPCR

This application note showcases a Droplet Digital PCR (ddPCR) workflow that can detect mutations commonly associated with non-small-cell lung cancer (NSCLC) in a single-well, 6-plex reaction.
A snippet of a DNA helix being captured
App Note / Case Study

Enhancing Precision in RNA-Seq with Target Enrichment

This application note describes a novel design strategy aimed at reducing bias and facilitating the discovery of novel fusion genes.
A scan image of a cancer infected set of lungs
App Note / Case Study

Future-Proof Your RNA-Seq Workflow

This application note describes the use of targeted custom RNA panels to overcome these challenges by enabling the robust and sensitive detection of gene expression profiles from FFPE non-small cell lung cancer samples.
A liquid handling robot transfers samples into a 96-well plate
App Note / Case Study

FFPE Sample Prep Advancements To Transform Solid Tumor Treatment

This case study presents a scalable, automation-friendly workflow for active deparaffinization, extraction and purification of nucleic acids from FFPE samples that can transform cancer diagnostics as demand grows.
A target focusing on an orange cancer cell amongst blue cells
App Note / Case Study

Smarter Fusion Detection for Cancer Diagnostics

This app note highlights a robust targeted RNA enrichment workflow that integrates automation to expedite library preparation and data analysis.
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