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Latest App Notes & Case Studies

Targeted Methylation Sequencing content piece image
App Note / Case Study

Targeted Methylation Sequencing

Download this app note to discover methylation capture panels that show excellent performance across a wide range of methylation targets, enable highly optimized designs out of the box and are compatible with enzymatic or bisulfite conversion.
Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes content piece image
App Note / Case Study

Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes

Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.
Enriching Pathological Analysis of FFPE Tumor Samples With Spatial Transcriptomics content piece image
App Note / Case Study

Enriching Pathological Analysis of FFPE Tumor Samples With Spatial Transcriptomics

Download this app note to discover how Visium Spatial Gene Expression can help verify and refine traditional pathologist-led analysis as well as characterize spatial gene expression patterns of known prostate cancer markers plus much more.
Optimize Cell and Gene Therapies With Single-Cell Multiomics content piece image
App Note / Case Study

Optimize Cell and Gene Therapies With Single-Cell Multiomics

One of the more promising types of cancer immunotherapy involves engineering immune cells to recognize and attack cancer.
Revolutionizing Drug Discovery in Hematological Oncology content piece image
App Note / Case Study

Revolutionizing Drug Discovery in Hematological Oncology

The approach to treating hematological malignancies is rapidly evolving as we discover the underlying mechanisms of disease and identify new immune pathways within the patient’s body to harness.
Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma content piece image
App Note / Case Study

Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma

Download this app note to discover how to distinguish tumor versus normal cells in a heterogeneous sample, reconstruct cell type–specific gene regulatory network
and confirm PAX5 as a critical regulator specific to tumor B cells.
Imaging Organoids With Light-Sheet Fluorescence Microscopy content piece image
App Note / Case Study

Imaging Organoids With Light-Sheet Fluorescence Microscopy

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms content piece image
App Note / Case Study

Accurate Quantification of Interferon Gamma Across Immunoassay Platforms

Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
Spatially Resolved Heterogeneity of Triple Negative Breast Cancer content piece image
App Note / Case Study

Spatially Resolved Heterogeneity of Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is unresponsive to traditional hormone or targeted therapies and highly heterogeneous. Improved understanding of the biological underpinnings and cell-type composition of TNBC is critical to developing novel targeted treatment options.
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis content piece image
App Note / Case Study

Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis

Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
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