Latest App Notes & Case Studies

App Note / Case Study
Targeted Methylation Sequencing
Download this app note to discover methylation capture panels that show excellent performance across a wide range of methylation targets, enable highly optimized designs out of the box and are compatible with enzymatic or bisulfite conversion.

App Note / Case Study
Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes
Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.

App Note / Case Study
Enriching Pathological Analysis of FFPE Tumor Samples With Spatial Transcriptomics
Download this app note to discover how Visium Spatial Gene Expression can help verify and refine traditional pathologist-led analysis as well as characterize spatial gene expression patterns of known prostate cancer markers plus much more.

App Note / Case Study
Optimize Cell and Gene Therapies With Single-Cell Multiomics
One of the more promising types of cancer immunotherapy involves engineering immune cells to recognize and attack cancer.

App Note / Case Study
Revolutionizing Drug Discovery in Hematological Oncology
The approach to treating hematological malignancies is rapidly evolving as we discover the underlying mechanisms of disease and identify new immune pathways within the patient’s body to harness.

App Note / Case Study
Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma
Download this app note to discover how to distinguish tumor versus normal cells in a heterogeneous sample, reconstruct cell type–specific gene regulatory network
and confirm PAX5 as a critical regulator specific to tumor B cells.
and confirm PAX5 as a critical regulator specific to tumor B cells.

App Note / Case Study
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.

App Note / Case Study
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.

App Note / Case Study
Spatially Resolved Heterogeneity of Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) is unresponsive to traditional hormone or targeted therapies and highly heterogeneous. Improved understanding of the biological underpinnings and cell-type composition of TNBC is critical to developing novel targeted treatment options.

App Note / Case Study
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis
Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
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