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Automated Parallel Capillary Electrophoresis for Purity Analysis of ssDNA and RNA Oligonucleotides

Automated Parallel Capillary Electrophoresis for Purity Analysis of ssDNA and RNA Oligonucleotides content piece image

Performance Characteristics of the Agilent Oligo Pro II System


As oligonucleotides (oligos) are synthesized, small amounts of impurities can be introduced at each step, and different synthesis methods and purification efficiencies can impact the quality of the sample. This means that assessment of the synthesized oligos is essential to ensure it is of the purity level needed for downstream applications such as PCR, gene assembly and microarray/hybridization assays.


Download this tech note to discover a system that can:


  • Provide high resolution and direct detection of oligo
  • Accommodate a variety of throughputs and allow for the analysis of 12, 24 or 96 samples simultaneously
  • Automate capillary conditioning, sample injection, electrophoresis separation and data processing
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