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Effortlessly Analyze Pyruvate Kinase Inhibitors

Pyruvate Kinase Inhibitor Measurements and Effortless Data Analysis Using the MARS Data Analysis Software


Pyruvate kinase is an enzyme involved in energy-supplying glycolysis and ATP synthesis, thus is pivotal for the eucaryotic energy metabolism. In addition, overexpression of pyruvate kinase is believed to play a role in cancer.

Elevated levels of the PKM2 isoform of pyruvate kinase can be used as a cancer marker and are associated with unfavorable prognosis. Accordingly, the development of pyruvate kinase inhibitors may offer new treatments for various cancers.


Download this app note to discover a platform that:

  • Absorbance detection of multiple wavelengths which allows comprehensive DNA quality assessment
  • Determination of DNA purity ratios in low volumes of only 2 ┬ÁL per sample
  • Analysis software which simplifies the calculation of DNA purity ratios
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