We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Latest Articles

Targeting TGF-β Signaling in Cancer: A Double-edged Sword
Article

Transforming growth factor (TGF)-β signaling is an attractive therapeutic target as it is deregulated in many cancers. But challenges remain around developing inhibitors that can specifically block tumor-promoting activities while preserving its tumor suppressive effects.

READ MORE

Mass Spectrometry is Advancing Cancer Research in Leaps and Bounds
Article

From picking out cancerous tissue areas during diagnosis, to uncovering novel biomarkers of early detection, mass spectrometry has become an indispensable analytical technique in cancer research.

READ MORE

Addressing the Underrepresentation of Women in Science
Article

We recently spoke with Jessica Wade, PhD, a physicist at Imperial College London to learn more about her extraordinary efforts to raise the profile of female scientists and other underrepresented groups in science.

READ MORE

Incentivizing Drug Development for Rare Diseases
Article

On Rare Disease Day 2019, we discuss how regulatory incentives are necessary for encouraging rare disease drug development, and share the testimonial videos from this year's international campaign.

READ MORE

Cell Metabolism and Cancer
Article

It’s almost 100 years since Otto Warburg’s observation that cancer cells metabolize glucose in a manner that is distinct from that of cells in normal tissues. Yet, we still don’t fully understand why. In the years since, significant effort and resource has focused on understanding cancer-specific metabolic changes. Today, attention is also turning to the metabolic interaction between a tumor and its host.

READ MORE

Pluripotent Stem Cells in Drug Discovery: Can We Stem the Tide of Unsuccessful Drugs?
Article

Stem cells were first discovered in human cord blood in 1978. Why would we think they can be of more help now? This article delves into reasons behind the sudden interest in stem cells, and highlights how they can be used to advance drug discovery.

READ MORE

How Genomics is Shaping Advanced Therapeutics
Article

Genomics technologies are guiding the development of advanced therapy medicinal products, i.e. gene-based, cell-based, and tissue-engineered approaches. This article highlights the progress, challenges and impact of this interdisciplinary branch of medicine.

READ MORE

Recent Advances in Liquid Biopsy for Cancer
Article

Liquid biopsies for cancer search for evidence of disease biomarkers, the most common of which include circulating tumor cells, cell-free nucleic acids, exosomes, proteins and phosphoproteins. Read on for insights on advances in the field that could revolutionize clinical oncology practice.

READ MORE

Overcoming Challenges in Biopharma: Transformational Innovation is Key
Article

Looking at the industry growth and the complexities of biopharma development, it is no wonder that transformational developments are required to better equip laboratories and operations in biopharma.

READ MORE

Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia
Article

Thanks to advances in therapeutics, chronic myeloid leukemia has been transformed from a deadly cancer into a manageable, chronic condition. However, patients have to stay on these drugs their whole lives, as there isn't a diagnostic test sensitive enough to detect traces of the disease that threaten a relapse. This article delves into the unmet need for such a test, and explains why droplet digital PCR (ddPCR) is a strong candidate that may fill this gap.

READ MORE