Latest Articles

The Changing Role of Pathologists in the Age of Precision Medicine
Article

We spoke to Dr Philippe Taniere, Consultant Histopathologist/Molecular Pathology, and Dr Matthew Evans, Specialist Registrar at University Hospitals Birmingham, to learn how the role of pathologists is changing, what this means for oncologists and cancer patients, and some of the challenges these changes may present.

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World Cancer Day: Unite the Fight Against Cancer
Article

World Cancer Day takes place on February 4 each year. This global event aims to ‘unite the fight’ against cancer and raise awareness of the disease. To mark this day, we have compiled some key cancer facts and a selection of the latest research developments.

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Reprogramming and iPSC Formation - Then and Now
Article

The ability to create stem cells from non-embryonic cells, through the process of reprogramming, lifted the ethical hindrance and is driving stem cell research in a new direction at a rapid pace.

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Liquid Biopsies Coming of Age
Article

Based on the analysis of cells, genes, and chemical signals in body fluids, liquid biopsies provide timely, actionable information on disease states while eliminating the high cost and risks of tissue biopsies. Gene amplification through polymerase chain reaction and related techniques offer these benefits with the added advantage of amplifying low-abundance species. This article looks at the state of the art in PCR-based liquid biopsies, including a discussion of the technique's limitations.

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The Cancer Moonshot 2020: Then, Now & the Future
Article

Since the launch of the project, patients, caregivers, doctors, cancer centers, regulators and others have been hard at work to drive cancer research and treatment forward in a race to beat the disease.

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Bioimaging Using Microscopes: Challenges, Benefits and the Future
Article

The imaging of biological samples, or bioimaging, plays a key role in current life science research, enabling scientists to analyze molecules, cells and tissues from a range of living systems.

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The MAPK Pathway as a Therapeutic Target in Cancer Research
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Following the rapid and striking success of vemurafenib, a MAPK targeting drug used to treat melanoma, interest in this critical cell signalling pathway has exploded.

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Uncovering the Role of H. pylori in Stomach Cancer
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An interdisciplinary team of researchers recently demonstrated the role that H. pylori plays in gastric stem cell renewal. We spoke to lead author, Professor Thomas Meyer from the Max Planck Institute for Infection Biology, to learn more about the study and its wider implications for the future diagnosis and treatment of stomach cancer.

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Quantitative Proteomics in Precision Medicine
Article

Medicine has been moving away from a "one-size-fits-all" approach towards predictive, preventive and treatment strategies tailored to the individual - precision medicine. Quantitative proteomics is playing an important part in this process but there are still some areas in which improvements must be seen before assays are likely to be routinely available to clinicians and patients.

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Isolating Exosomes for Cancer Diagnostics
Article

Exosomes offer a promising avenue for the minimally invasive diagnosis and monitoring of a range of cancers. Overcoming the challenges of isolating these small vesicles from biofluids could lead to wider adoption of exosome technologies in the clinic, and eventually translate into earlier detection and improved treatment plans for cancer patients.

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