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Cell Potency: Totipotent vs Pluripotent vs Multipotent Stem Cells
Article

Here we discuss the differences between totipotent, pluripotent, and multipotent stem cells.

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Henrietta Lacks: The Mother of Modern Medicine
Article

A portrait of Henrietta Lacks has recently been unveiled at the Smithsonian’s National Portrait Gallery, to recognize her life and the vital contributions HeLa cells have made to science.

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How Mass Spectrometry Has Changed the Cancer Diagnostics Game
Article

Although histopathology is still the gold standard for diagnosing cancer, molecular analysis using MS has gained traction in recent years for detecting tumors, monitoring progression, and even predicting treatment response.

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Exploiting the Tumor Microenvironment for Cancer Therapeutics
Article

It’s more than a century since Paget first proposed the ‘soil and seed’ hypothesis in cancer, providing evidence that the environment surrounding a tumor is as important as the tumor itself. Research in this area has gathered momentum and it’s now the focus of intense research efforts.

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Tumor-extrinsic Immune Evasion in the Tumor Microenvironment
Article

Until now, tumors have been considered wholly responsible for an unpredictable and highly variable immune evading tumor microenvironment. Using genetically engineered animal models researchers now demonstrate that individual-specific receptor variants can shape the composition of the tumor neighborhood irrespective of the tumor types.

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Will Microfluidic Cell Culture Fulfill its Long-awaited Potential?
Article

The first paper ever published on microfluidic cell culture is 19 years old. Microfluidic cell culture has now outgrown its infancy and is about to survive its teenage years. It has matured considerably but still needs to transition from academia into clinics and industry. Will it come of age?

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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Catching Cancer Early: How Improving Cancer Awareness Can Prevent Delayed Diagnosis
Article

When it comes to cancer detection and diagnosis – the earlier the better. Cancer that remains undiagnosed until it is within ‘advanced’ stages is harder to treat successfully.

15-40 Connection’s mission is to empower patients and promote cancer conversation to ultimately improve cancer survival rates.

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Relaxing the Tension Between Publishing and Patenting: Practical Hints and Tips
Article

In Part 1 we outlined some patent-related ramifications of publishing your research and development prior to filing a patent application. This second part provides you with some practical hints and tips for drafting your paper, helping you to avoid potential issues that can arise.

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Relaxing the Tension Between Publishing and Patenting: The Legal Basis for Tension
Article

Tension can be felt between the desire to publish and the need to patent, especially in commercially savvy environments such as medical technology and pharmaceuticals. This article discusses the legal rationale behind why publishing early can hinder future patenting opportunities and provides practical tips for avoiding this situation.

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