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Meet the Culprits of Cell Culture Contamination

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Cell culture contamination is a problem on many levels, creating immediate implications for experiments and wider issues for the scientific community.

Missense, Nonsense and Frameshift Mutations: A Genetic Guide

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If you want to build a foundational understanding of genomics in both health and disease, it's important to be able to distinguish between the different type of genetic mutations that can occur. Here, we take a look at some of the mutations that can be encountered and the impact they have on the genome.

Exploring the Medicinal Benefits of Cannabis Within UK Pharmaceuticals

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In this article, we explore how the use of cannabis within UK pharmaceuticals is expected to change, as well as the medicinal benefits offered by cannabis, and cannabinoids.

The Importance of Understanding Target–Protein Interactions in Drug Discovery

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You’re unwell, you see a doctor, they prescribe you a medicine… and you take it. But how exactly is that drug having an effect? What is its mechanism of action? Drugs exhibit their effects through specific protein–target interactions. Andrew Lynn, Chief Executive Officer at Fluidic Analytics discusses why understanding protein–target interactions is so important.

Liquid Biopsy: Guide, Applications and Techniques

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Liquid biopsies are tests conducted on blood samples that examine biomarkers shed by tumors, such as cancer cells or pieces of tumor DNA. The data from liquid biopsies can be used in place of or alongside that of traditional surgical biopsies. In this article, we review the theory behind liquid biopsies and their applications in cancer medicine.

The Pursuit of Spotting and Steering Cell Death

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Here, we examine one common branch of cell death, apoptosis, and explain why studying aberrations in apoptotic signaling is important for understanding and addressing a range of human pathologies. We also highlight techniques that enable studies of apoptosis.

Future Cancer Immunotherapy Treatments Could Be Administered by a Pill

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Immunotherapies delivered in pill form aren’t yet the default cancer treatment. Techniques like protein painting are bringing that day closer.

Advances in PCR Diagnostics for Cancer and Medical Mycology

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From detecting cancer to microbial infections, and now even fungal infections, PCR has become the gold standard of analyzing gene expression. In this article, we explore how PCR is used as a novel diagnostic strategy to identify clinically important yeast species, as well as to detect mutations that could guide therapeutic decisions for lung cancer patients.

Cell Culture Workflows In a Spin? How Next-generation Centrifuges Are Overcoming Common Challenges

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In this article, we discuss the challenges scientists face when employing conventional benchtop centrifuge systems, and explain how the latest technological advances are helping laboratories to overcome them, allowing organizations to improve efficiency and achieve more reliable results.