Latest Articles
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Developing Novel Cell Therapies by Rewiring T-Cell Genomes
In a recent Teach Me in 10 episode, Dr. Theo Roth discussed what targeted pooled knock-in screens are, how he is working to accelerate the discovery of cell-based therapies and how this process could reduce the time it takes to transition these therapies from the lab to the clinic.
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Neuroimaging Techniques and What a Brain Image Can Tell Us
In this article, we will cover the basics, strengths and limitations and applications of traditional and emerging neuroimaging techniques, and discuss the prospects, challenges, risks and ethics concerned with this rapidly expanding field.
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What Is Angiogenesis?
Angiogenesis is the growth of new blood vessels. However, this process is often dysregulated in cancer. In this article, we will describe what angiogenesis is, how it goes out of control in cancer and how drugs can target it to inhibit tumor growth.
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Immunohistochemistry Techniques, Strengths, Limitations and Applications
Immunohistochemistry exploits antigen–antibody binding to study the status of target molecules in tissues of interest. In this article, we explore how it works, factors that impact experimental design and its applications.
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An Introduction to Electroporation – A Tool for Transfection and Competent Cell Generation
There are many reasons you may want to deliver something into a cell, be it genetic material or a therapeutic drug, and electroporation is a vital tool to achieve this. In this article, we will consider what electroporation is, how it works and how it’s used.
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Mapping the Body’s Defense System: The Immune Cell Atlas
This article will provide an introduction to the Immune Cell Atlas, highlight some of the research contributing to the project and explore the wider implications of the work.
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Principal Tools Uncovering Complexities of Novel Drug Target Discovery
In this article, Dr. Kenneth Oh discusses how a comprehensive qPCR–western blot–multiplex assay workflow can revolutionize drug discovery approaches.
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Patient-Derived Organoids Predict Chemotherapy Efficacy for Pancreatic Cancer
Technology Networks had the pleasure of talking to Dr. Matthew Weiss to learn more about patient-derived organoids and how these disease models could be used to develop personalized treatment strategies for pancreatic cancer.
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Rewiring T Cells To Enhance Immunotherapy Efficacy
Researchers have identified a modifier gene called lymphotoxin beta receptor (LTBR) – which is not normally expressed in T cells – and combined it with CARs to create T cells that were better equipped at killing tumor cells.
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Cell Culture Quality Control: The Key to Reproducibility
This article will outline four main aspects of QC in cell culture and describe what they are and why we should carry them out.
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