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Generating robust organoids for the lung and gastrointestinal system to recapitulate the complex organ environment remains challenging. Quality growth factors (GFs), such as EGF, FGFs, Noggin, BMP, and RSPO1, are essential in this process. FGF10, HGF, and KGF/FGF7 have been shown to synergistically promote the formation of bronchioalveolar and alveolar organoids. FGF2 and IGF-1 also enhance intestinal organoid plating.

Ductal carcinoma in situ (DCIS), cancer cell growth that starts in the milk ducts, is the most common form of breast cancer. However, why some DCIS progress to invasive carcinoma but others remain innocuous is still unclear. In a recent study, three groundbreaking technologies—Chromium Single Cell, Visium Spatial, and Xenium In Situ—were used to achieve a deeper understanding into the biology of a single, breast cancer patient-derived, FFPE tissue block.

With tools like Visium Spatial Gene Expression, researchers can access a multidimensional profile of the biology of a complex tissue section, measuring and mapping spatial gene expression while maintaining a clear view of the morphological context of the tissue.

The Uniqsis ColdChip™ is a new versatile mixer/reactor module enabling researchers to experiment with different chemistries particularly exothermic reactions that need to be safely run in a cooled environment with highly efficient mixing. Compact in design, and requiring no input power, the ColdChip™ is optimised for use with the Uniqsis FlowSyn and FlowLab range of flow reactors as well as standalone pumps.

The timsTOF HT, a novel 4th-generation TIMS (trapped ion mobility separation) XR cell and 14bit digitizer for even greater dynamic range, enhanced peptide coverage and more accurate quantitation, particularly in unbiased 4D plasma and tissue proteomics and epiproteomics.

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. This system offers the most efficient methylation detection available.

Sino Biological has developed a panel of recombinant IFN-γ protein and receptors reagents to support the study of IFN-γ in cancer immunity.

4Cell® Nutri-T GMP is the ideal culture medium for the development and scale-up of T cell-based therapeutic immunotherapy and cell therapy applications. It is the only medium that does not require the addition of serum, hence simplifying the process, and is more compliant with regulatory requirements.

Defined, xeno-free, serum-free cell culture medium designed to support the growth and expansion of human induced pluripotent stem (hiPS) and human embryonic stem (hES) cells.

A salt-based, chemically defined, animal component-free, protein-free cryopreservation solution. Contains 5% DMSO.