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Overcome Roadblocks to PROTAC Characterization

heterobifunctional molecules
Credit: Nanotemper

Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that offer a promising therapeutic strategy against hard-to-treat diseases. Unlike traditional small molecule inhibitors, developing PROTACs presents unique challenges — particularly the characterization of binary and ternary complexes. 

This guide highlights how an innovative, plate-based, and automation-ready affinity screening solution helps you overcome roadblocks in your PROTAC characterization projects.

Download this guide to discover a platform that helps you: 

  • Characterize ternary complexes, covalent binders, or small molecules without immobilization
  • Take in-solution and mass-independent affinity measurements
  • Reduce sample consumption while maintaining exceptional data quality

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