Targeted Protein Degradation: A Promising Therapeutic Strategy for the Most Challenging Protein Targets

Targeted protein degradation (TPD) is getting a lot of attention as a new and promising modality to treat a variety of diseases from cancer to Alzheimer’s. By taking proteins down the cell’s own degradation pathway instead of the typical inhibition approach, TPD allows researchers to develop successful therapies that address previously undruggable targets due to the absence of defined binding sites. 

Download this infographic to learn more about:

• Inhibition and degradation approaches in drug development
• The advantages and challenges related to each approach
• The key points you need to consider when designing your protein degraders