3D Cell Culture: Miniature Dimensions Drive Massive Advances

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Published: December 14, 2020

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3D Cell Culture: Miniature Dimensions Drive Massive Advances content piece image

Credit: Geoffrey Wahl, Christopher Dravis, National Cancer Institute/Salk Institute

Cell culture has been advancing biological and biomedical research since the first cell line was established in the late 1940s. Cells have mostly been cultured in a two-dimensional (2D) format as a monolayer adhered to a dish or plate well. In the past two decades, however, researchers have begun to switch gears, transitioning away from 2D in favor of three-dimensional (3D) cultures.

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Various 3D cell culture formats
Key research areas that have harnessed 3D cultures

Meet the Author

Masha Savelieff, PhD

Masha Savelieff is a professional freelance scientific writer. She began her science career in chemistry at the American University of Beirut in Lebanon, where she earned her BSc and MSc degrees. She then went on to receive her PhD, also in chemistry, from the University of Illinois in 2008. Masha then branched out into biology and biomedical research by completing her postdoctoral training in Alzheimer’s disease at the University of Michigan. Finally, she widened her biology experience in cancer research and metabolic disease, also at U-M. Masha now writes full-time on a breadth of scientific topics.