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Cancer Cell Line Choice: 3 Considerations to Make

Cancer Cell Line Choice: 3 Considerations to Make content piece image
HeLa cells - the oldest and most commonly used human cell line. The line was derived from cervical cancer cells taken in 1951 from Henrietta Lacks, a patient who eventually died of her cancer. Credit: Tom Deerinck, NIGMS, NIH

In vitro experiments are a mainstay of cancer research. However, it is crucial to select the appropriate cell line to yield meaningful insights from in vitro experiments. The cell line should reflect the type of cancer under scrutiny and should also be able to address the questions posed by the experiments.

Download this list for tips on:

  • Selecting your cell lines
  • Checking on your cell lines
  • Minimizing variability in your cell line experiments