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Researchers Find Better Treatment for Rare Pregnancy-Related Cancer

Scientists have found a way to combat a rare, aggressive form of cancer affecting pregnant women and to better ensure the drug used for the disease reaches tumor cells without damaging healthy tissue.
A needle piercing a vaccine vial.
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Cancer Vaccine Shows Promise for Advanced Kidney Cancer

A phase 1 trial of a personalized cancer vaccine for stage III/IV clear cell renal cell carcinoma showed promising results. The vaccine trained patients’ immune systems to target cancer cells, preventing recurrence.
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Mutations Point to Promising Drug Target in 5% of Adult Cancers

Researchers have discovered that about 5% of adult cancers rely on a gene called PELO to survive, offering a promising drug target.
Two side-by-side microscope images, illustrating how cancer cells invade.
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Study Follows Stem Cells as They Transform Into Oral Cancer Cells

Researchers have discovered how healthy stem cells are transformed into cancer stem cells in the early stages of oral cancer.
A cancer cell, with surface proteins visible.
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Antibody Drug’s “Outside-In” Signal Shows Route Into Cancer Cells

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell.
Cancer stem cells.
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Potential New Childhood Brain Cancer Holds Promise Against Treatment-Resistant Tumors

A new study reveals that the experimental drug CT-179 targets OLIG2-positive cancer stem cells, preventing tumor recurrence in medulloblastoma. Preclinical trials show the drug crosses the blood-brain barrier and enhances radiotherapy.
A clinician in a lab coat holds a holographic screen illustrating how AI can benefit healthcare.
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Study Reveals Accuracy of AI-Supported Breast Cancer Screening

New results indicate that AI-supported breast screening can detect 29% more cancer cases than traditional screening.
Cancer cells.
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Blocking Tumor Growth Before It Starts

SickKids researchers have identified OLIG2, a protein that activates stem cells driving medulloblastoma, the most common childhood brain cancer. Blocking this protein with CT-179 prevented tumor formation and relapse in preclinical models.
Cell therapy.
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Study Finds No Evidence CAR T-Cell Therapy Causes Secondary Cancers

A study of 783 patients treated with CAR T cell therapy found no evidence that the therapy itself caused secondary cancers. Researchers confirmed that rare cases of cancer were linked to prior treatments like chemotherapy, not CAR T therapy.
A month's supply of a contraceptive pill in a blister pack on a blue background.
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Could the Contraceptive Pill Reduce Ovarian Cancer Risk?

The contraceptive pill may reduce ovarian cancer risk by up to 43% in women over the age of 45, reports a new study.
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