News

New research may provide a new biological target for immunotherapies designed to destroy spreading cancer cells that are often markers for worsening disease.

A identified 813 potential cancer driver genes via splicing, expanding targets beyond traditional mutation-centric models. Using the "spotter" algorithm, researchers found significant non-overlap with existing mutation databases.

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue.

Researchers developed Spacia, a computer model that improves detection of cell-to-cell communication (CCC) using spatially resolved transcriptomics data. Spacia, which uses multi-instance learning, provides deeper insights into diseases.

A novel drug could be used to tackle aggressive drug-resistant prostate cancers that do not respond to conventional therapies.

Researchers have pioneered a light-based method for analyzing dried blood crystals, enhancing cancer detection. The technique shows 90% accuracy in diagnosing and classifying cancer with less pain and risk compared to traditional methods.

Research uncovers how cancer cell nuclei deform when migrating through narrow channels. The study shows that nuclear shape changes through a biphasic process influenced by cytoskeletal forces.

A study investigating the effects of fasting and the ketogenic diet has revealed a new vulnerability of pancreatic tumors to a cancer drug currently in clinical trials.

Researchers found that androgen deprivation therapy (ADT) for prostate cancer may increase Alzheimer’s risk by damaging the blood-brain barrier and promoting brain inflammation.

Researchers have developed MS-41, an innovative anti-cancer degrader. This compound targets and degrades the ENL protein, crucial for MLL-rearranged leukemia in infants.