Probing Deep Into Tumor Tissues
Researchers have analyzed more than 8,000 proteins in detail from fixed samples of lung cancer tissue using mass spectrometers.
Most Cancer Cells Grown in a Dish Lack Similarity to Those in People, Suggests Study
Johns Hopkins Medicine researchers report they have developed a new computer-based approach showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.
Novel Drug Class Could Treat Various Cancers With Faulty BRCA Genes
Scientists have identified a novel class of targeted drugs that offer the potential to treat patients whose tumors possess faulty copies of the BRCA cancer genes.
Metabolic Processes Visualized at the Single-Cell Level
Researchers at the University of Chicago's Pritzker School of Molecular Engineering and Biological Sciences Division have developed a combined imaging and machine learning technique that can, for the first time, measure a metabolic process at both the cellular and sub-cellular levels.
Immune Cells Tricked Into Helping Tumors Invade the Lungs
Scientists have found that macrophages can be fooled by tumors when cancer starts forming in the lungs and help the tumor become invasive.
“Enabler Cells” Inside Tumors Can Trigger Metastasis
Research has shown that a small number of "enabler cells" found in tumors can enable and recruit other types of cells nearby, allowing the cancer to metastasize.
Exploiting the Body's "Natural Killers" To Target Breast Cancer
Researchers are using a bifunctional protein as a "bridge" between natural killer cells and breast cancer cells. This strategy could help to develop a novel breast cancer-specific immunotherapy.
A New Path Towards Brain Tumor Therapy
Researchers have shown that the nucleoside transporter ENT2 may offer a path to circumvent the blood-brain barrier and enable targeted treatment of brain tumors.
Cancer Cells Use an Aging Gene to Their Advantage
Researchers have discovered how mutated cells promote their chances in order to form cancer.
Discrepancies in the Reference Human Genomes Are Identified
Researchers have identified genetic variant discrepancies between the two human reference genomes, creating guidance for laboratories to take advantage of an improved human reference genome.