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Targeting the Circadian Rhythm Regulator CRY-1 in Prostate Cancer
News Jan 18, 2021A regulator of circadian rhythms, known as CRY-1 has been shown to promote tumor progression by altering DNA repair.
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Biochemical Pathway Discovered That Protects Cells From Ferroptosis
News Jan 15, 2021In an article published in Cell Metabolism, Moffitt Cancer Center researchers report on a newly discovered biochemical pathway that protects cells from a type of cell death called ferroptosis.
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Drug May Reduce Tumor Volume in Neurofibromatosis
News Jan 15, 2021Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).
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Drug Combo for Rare Form of Cancer Shows Promise in Cell-Based Study
News Jan 15, 2021A rare form of lymphoma called Waldenström macroglobulinemia (WM), currently has no known cure and only one FDA-approved treatment. Researchers have now targeted specific cell proteins that control DNA information using inhibitors, that were effective in reducing the growth of the cancer cells. When combined with a third drug the combination was even more successful at killing the WM cancer cells.
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Cancer Researchers Reveal How Mutations in a Single Gene Can Cause Different Diseases
News Jan 15, 2021Researchers report that they have solved a long-standing question of how various types of mutations in a single gene can cause different types of disease. Their findings were published in Life Science Alliance.
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UV Radiation Causes Rare Type of Eye Cancer
News Jan 14, 2021Ultraviolet radiation can cause a rare type of eye cancer called conjunctival melanoma, according to research published in Nature Communications.
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Painting a Clearer Picture of the Cancer Microbiome
News Jan 14, 2021Researchers have created an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). This will enable scientists to identify the microbiota living in various organs in both healthy and cancerous states more accurately.
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Investigating the Role of a Key Metabolic Pathway in Melanoma
News Jan 13, 2021Disrupting the metabolic pathway involved in the initiation, growth and progression of melanoma could lead to the development of new treatments for melanoma, according to new research published in PLoS One.
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Enzyme in Tumor Cells Could Be Used To Monitor Cancer Treatment
News Jan 13, 2021Researchers are studying the possibility of inhibiting a protein known as low molecular weight protein tyrosine phosphatase (LMWPTP) to create novel opportunities for monitoring and treatment of cancer and other diseases.
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Stem Cells Use a Piston-Like Engine To "Drive" to Their Destinations
News Jan 12, 2021Researchers have discovered the surprising propulsion system that enables these regenerative cells to migrate through surrounding tissue to repair damage.
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