News

In high-risk groups, Kaposi's sarcoma-associated herpesvirus (KSHV) can trigger aggressive cancers. Research has shown how KSHV drives cell metabolism and proliferation. Inhibiting this process can block lymphoma progression and shrink existing tumors in preclinical models.

A new study finds precancerous colon cells turn on a gene called SOX17, which helps them evade detection and develop into more advanced tumors.

Scientists from the Keck School of Medicine of USC conducted one of the largest multiethnic studies to date of smoking and epigenetics, research that could eventually lead to better ways to predict smoking-related disease risk.

A signature of bacterial strains in the gut microbiome may be able to identify cancer patients that will respond well to certain immunotherapy drug combinations, according to a new study from Wellcome Sanger Institute and Olivia Newton-John Cancer Research Institute researchers.

Many cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved through expedited (“fast track”) pathways, finds a study published by The BMJ.

Patients with cancers that are immunologically "cold" still produce cancer-fighting T cells and therefore may benefit from personalized immunotherapy.

New research points to a streamlined approach to drug discovery that allows drug makers to determine the viability of a fragment-based design earlier in the process.

CSHL scientists discovered that early pancreatic cancer cells depend on the regulators of mucus production to survive and grow.

Imagine if we could inhale scents that delay the onset of cancer, inflammation, or neurodegenerative disease. Researchers at the University of California, Riverside, are poised to bring this futuristic technology closer to reality.

A study recently published has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.