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Mechanism of Platinum Drug Resistance in Colorectal Cancer Identified

A new study has shown that platinum-based chemotherapy drugs, used to treat some colorectal cancers, can accumulate in surrounding healthy cells and reduce the tumor's sensitivity to treatment.
Cells stained pink and purple.
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Promising Targeted Drug Identified for Rare Leukemia

A promising targeted drug has been identified that could be effective against rare, hard-to-treat leukemias.
A hand holding a plastic anatomical model of a kidney.
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Genetics Reveal Risk of Kidney Cancer Returning

New research has linked the genetic changes that occur in kidney cancer to patient outcomes, and could be used to better predict the risk of the disease coming back.
Mistletoe with white berries.
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Trial Investigates Mistletoe Extract as Possible Cancer Treatment

Mistletoe extract has been widely used to support cancer therapy and improve quality of life, but there has been a lack of clinical trials and data to support its use until a recent trial from Johns Hopkins Kimmel Cancer Center.
Breast cancer cells stained in haemotoxylin and eosin, viewed under the microscope.
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"Fingerprinting" Calcium Deposits May Provide Information on Cancer

A new study has characterized “fingerprints” in calcium mineral deposits (microcalcifications), revealing pathological clues to the progression of breast cancer and potentially other diseases.
A scan of a fetus over a pregnant belly.
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Key Processes During Fetal Development May Protect Against Leukemia

During the fetal stage, a number of cell programs run that are vital to the development of the fetus. Researchers from Lund University have demonstrated that one of these fetal programs appears to protect against leukemia.
Human lymphoma cells seen under the microscope.
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Whole Genome Sequencing Sheds Greater Light on Hodgkin Lymphoma

A new study has highlighted the benefits of whole genome sequencing of classic Hodgkin lymphoma over exome sequencing.
An image of cells.
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Third Patient Becomes “HIV Free” After Stem Cell Therapy

A 53-year-old male patient in Düsseldorf is the third person to achieve long-term human immunodeficiency virus type 1 (HIV-1) remission after receiving a stem cell therapy. The case study is published in Nature.
A closeup of a hand with a peripheral IV.
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Molecular Marker Predicts Recurrence of Aggressive Brain Tumors

According to research, the loss of a single copy of CDKNA/B genes can significantly accelerate the recurrence of aggressive meningiomas.
Light microscope image showing the liver of a diseased mouse in which many tumors have formed.
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Iron-Dependent Cell Death Could Be Key to Liver Tumor Treatment

A new study has identified three substances that can fight tumour growth and reduce liver metastases.
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