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Protein Key to Tumor Cell Metabolism and Immune Evasion Identified
Tumor cells can alter their metabolism, and in doing so, dampen the body's anti-cancer immune response. A research team has identified a potential target for therapies in the protein key to this metabolic shift.
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Reengineering of Cancer Drugs Increases Their Versatility
Researchers have discovered a way to further tap the therapeutic potential of proteolysis targeting chimeras (PROTACs), small molecules used in cancer treatment and other conditions.
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AI With Infrared Imaging Enables Precise Colon Cancer Diagnostics
Researchers are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
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“Gatekeeper” Mutations May Help Resistant Cancers Come Back Stronger
A new study could explain why cancers stop responding to kinase inhibitor drugs and why they come back stronger.
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Blood Cancer Exploits Immune Cells for Survival
A comprehensive study of Hodgkin lymphoma has found that cancer cells use signals to manipulate the immune system in order to survive.
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Prediction Model Identifies Those at High-Risk for Endometrial Cancer
Researchers have developed a predictive model that could eventually be translated into clinical settings to identify high-risk individuals who would benefit from screening for endometrial cancer.
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Level of DNA Damage Similar for Vapers and Smokers
A group of researchers from the Keck School of Medicine of USC analyzed epithelial cells taken from the mouths of vapers, smokers, and people who had never vaped or smoked. They found that vapers and smokers had similar levels of DNA damage, more than twice the amount found in non-users.
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Previously Unknown Cell Mechanism Could Help Counter Cancer and Aging
In a new study, researchers discovered an unknown mechanism of how cells "remember" their identity when they divide – the cells' so-called epigenetic memory.
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Pancreatic Cancer Rates Rising Faster in Women Than Men
Researchers have confirmed that rates of pancreatic cancer are rising faster among younger women, particularly Black women, than among men of the same age.
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Possible Strategy To Induce Cancer Cell Death Revealed
Activation of p53 – the most commonly mutated tumor suppressor gene – has been shown to temporarily stop tumor growth, and new research has identified that inhibiting p53 repressors offers a potential mechanism of inducing cancer cell death.
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