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Melanoma Clinical Trial Reveals Success of Drug Combination

A combination of a common immunotherapy drug with all-trans retinoic acid, a chemotherapeutic, has shown promise in clinical trials.
Artistic recreation of a cancer cell undergoing mitosis.
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Population of “Cheating” Cancer Cells Identified by Researchers

Researchers have identified that some cancer cells can “cheat” by escaping constraints imposed by hypoxia, allowing the cancer cells to continue to grow.
Multiplex immunofluorescence image of hyaluronan-rich human colorectal cancer. Highly aggressive tumoral cells (turquoise and magenta) are negative for both aPKCs (yellow). The hyaluronan deposition in the stroma is labeled in green, and nuclei in blue.
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Potential Therapy for Colon Cancer Subtype Identified in Preclinical Models

A new study has demonstrated a promising experimental therapy in preclinical models of an aggressive subtype of colorectal cancer.
Artistic recreation of a cancer cell and lymphocytes.
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Why Hard-To-Treat Breast Cancers May Not Respond to Immunotherapy

Researchers have discovered how some cancers persist after chemo and why they don’t respond well to immunotherapies designed to clear out remaining tumor cells by revving up the immune system.
This image shows pancreatic cancer cells (nuclei in blue) growing as a sphere encased in membranes (red).
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New Target Genes Identified in Battle Against Pancreatic Cancer

Researchers from the Tokyo Medical and Dental University have identified potential targets for drug development against pancreatic cancer.
mRNA Cancer Vaccine Improves Survival Rates in Melanoma content piece image
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mRNA Cancer Vaccine Improves Survival Rates in Melanoma

A new personalized cancer vaccine has demonstrated efficacy against melanoma in a Phase IIb clinical trial.
Breast cancer cells.
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New Method Predicts Efficacy of Common Breast Cancer Drug

A biomarker has been identified that can be used to predict the efficacy of a chemotherapeutic commonly used to treat breast cancer.
3D render depicting blood vessel growth and the microenvironment around a tumor.
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Links Between Obesity and Breast Cancer Development Explored in Mouse Study

Focusing on breast cancer after menopause, a new study using mouse models suggests that obesity may cause previously dormant tumors to form new blood vessels, enabling them to grow and become more of a threat.
A cell-by-cell tapestry of prostate cancer progression.
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Cells Identified That May Promote Treatment Resistance in Prostate Cancer

A murine study has revealed that in prostate cancer, the expansion of castration-resistant cells correlates with resistance to treatment and poor clinical outcomes in humans.
A person running along a road.
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Exercise Raises Levels of Anti-Cancer Proteins, Even in Advanced Cancers

A single bout of exercise can raise the levels of myokines – proteins that are produced by skeletal muscles that can suppress cancer growth – in advanced cancers.
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