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Engineered T Cells Could Help Children With Treatment-Resistant Leukemia
Researchers at UCL and Great Ormond Street Hospital for Children (GOSH) have engineered donor T-cells to try and treat seriously ill children with resistant leukemia, who had otherwise exhausted all available therapies.
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Subset of Melanoma Patients Identified With Low Risk of Death
A subset of melanoma has been identified as having a low risk of death, which researchers hope could lead to a reclassification of the disease.
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Nobel-Winning "Click" Chemistry May Help Treat Bone Cancer in Dogs
Click chemistry, which recently earned a Nobel Prize, may efficiently deliver radioactive cancer treatments to tumors in dogs while reducing side effects.
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Vaccine Generates Immune Response Against Breast Cancer in Trial
Researchers in a new study describe the development of an experimental vaccine that could be used to prevent or treat an aggressive form of breast cancer, safely generating an immune response against an important driver of breast cancer growth.
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Discovery Boosts Potential of New Cancer-Fighting Drugs
Researchers have uncovered a critical feature that a promising new class of cancer drugs, known as CELMoDs, needs to be effective.
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Senescent Cell “Vaccine” Reduces Tumor Development in Cancer Models
Researchers have used senescent cells as a "vaccine" that can be used as a prophylaxis and a therapeutic to prime the immune system against cancer cells, which has shown positive results in cancer models.
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Programmable DNA “Nanotransporters” Could Improve Cancer Treatment
A new class of drug transporters have been created from DNA and are 20,000 times smaller than a human hair, in a discovery that could improve treatment for diseases like blood cancer.
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Metastatic Potential Increases for Cancer Cells in Highly Viscous Environments
Scientists have discovered how cancer cells exposed to high viscosity environments change the way they move to improve their invasiveness and favor metastases.
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Potential Drug Targets Discovered for Rare, Deadly Nerve Tumors
Researchers have used single-cell analyses to discover a new cell type that drives the progression of malignant peripheral nerve sheath tumors, finds ways to control that cell’s function and demonstrates treatment success in mice.
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"Genome Guardian” p53 Continuously Protects Our Cells From Tumorigenesis
Researchers have discovered that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their genomes.
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