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Identifying Undiagnosable Cancers Using Machine Learning
Researchers have developed a new deep-learning approach that may help classify cancers of unknown primary location, by taking a closer look at how their gene expression is related to early cell development and differentiation.
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Motion of Chromatin Can Help Facilitate DNA Repair
Researchers have discovered that chromatin around the site of DNA damage moves much faster to improve the accuracy of DNA repair.
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Landmark Genetic Study Aims To Wipe Common Childhood Cancer Off the Map
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Now, researchers at the St. Jude Children’s Research Hospital have created a roadmap of the genetic mutations present in patients with ALL.
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Inhibiting Key Enzyme Selectively Kills Melanoma Cells, Study Shows
Researchers have shown that inhibiting a metabolic enzyme, called glutaryl-CoA dehydrogenase, selectively kills melanoma cells and stops tumor growth.
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Cancer Cells That Survive After Treatment Lead to Relapse
Cancer recurrence can be due to a population of drug-resistant "persister" cells surviving chemotherapy. Researchers have now identified how these persister cells form.
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Drug Combination Halts Tumor Growth and Resistance in Mice
An experimental combination of two drugs in mouse models halts the progression of small cell lung cancer, findings that may lead to better treatments for the deadliest form of lung cancer.
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Anticancer Drug Produced by Reprogrammed Yeast
Researchers have used genetically engineered yeast to synthesize a chemotherapeutic drug that is susceptible to supply shortages.
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Astronauts May Be at Risk for Heart Disease and Cancer-Causing Mutations
According to research, astronauts are at higher risk for developing mutations that can increase the risk of developing cancer and heart disease.
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New Preclinical Mouse Model May Accelerate Thymus Gland Cancer Research
A new preclinical model for thymic cancer has revealed insights into how a common mutation found in thymic epithelial tumors sparks their formation.
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Accumulation of Nucleus Protein Fascin in Cancer Cells May Halt Their Spread
Researchers have shown that in cancer cells, a protein called fascin is transported into the cell nucleus where it plays an important role in cell motility and growth, providing insights into potential pathways that could block its action.
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