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Therapeutic Viruses Prime the Immune System To Fight Cancer

Researchers describe how oncolytic virotherapy, a technique using cancer-fighting viruses, can act together with existing immunotherapies, boosting the ability to target and destroy cancer cells.
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New Immunological Therapy for Chronic Hepatitis B and D Infections

A new treatment against hepatitis B and D viruses has shown promising results in animal models.
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New Target Identified for Triple-Negative Breast Cancer Treatment

Clinical data analysis has revealed that the nuclear receptor TLX could provide a new target for therapeutics to treat triple-negative breast cancer.
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A CRISPR-Based Test Could Help Clinicians Diagnose Heart Attacks and Cancer

A new method that increases the signal from CRISPR-based diagnostic tests, removing the need for amplification of DNA or RNA in a sample, could be used to quickly diagnose heart attacks and differentiate between cancer types.
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Study Shows Fertility Preservation Measures Do Not Increase Breast Cancer Recurrence

A Swedish study has shown that women with breast cancer undergoing procedures for fertility preservation are not at increased risk of cancer recurrence, giving hope to women who want to preserve their fertility after chemotherapy.
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Childhood Liver Cancer "Signatures" May Help Predict Response to Chemo

Researchers have used single-cell analysis tools to investigate liver cancer samples from children under age four, identifying five tumor signatures that may predict responses to chemotherapy treatments.
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Treatment Outcome and Resistance Markers Identified in Triple Negative Breast Cancer

Researchers have identified biological markers in triple-negative breast cancer that are associated with resistance to chemotherapy treatment.
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New Class of Chemotherapy Drugs For Safer, Targeted Leukemia Treatment

Researchers have identified two compounds that are more potent and less toxic than current leukemia therapies and could form the basis of an entirely new class of drugs.
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Altered Protein Promotes Aggressive Stem Cell-Like Changes in Breast Cancer

A change in function in a mitochondrial antioxidant protein increases stem cell gene expression, in turn promoting the development of more aggressive cancerous cells, according to a recent study by Northwestern Medicine researchers.
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Repurposed Drug Can Target Cancer Cells' Shield Against Immune System

Tumor cells use a protective coating of adenosine that disables the immune system – but researchers have found a drug already approved for other purposes can render this weapon harmless, potentially paving the way for new anti-cancer drugs.
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