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Aspirin May Help Slow Down Colorectal Cancer Evolution
Researchers have shown that taking aspirin can help protect against developing cancers of the colon and rectum by changing the way these cancer cell populations evolve over time, making them less able to survive and proliferate.
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Stress Protein Could Be a Good Target for Future Cancer Drugs
Inhibiting a stress protein that is upregulated in many different cancer types could provide a new strategy for future cancer drugs.
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AI Distinguishes Cancer Cells From Healthy Ones
A machine learning program has been used to distinguish between cancerous and healthy cells by identifying patterns in characteristic combinations of genes.
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Large-Scale Proteomic Study Finds 11 Pan-Cancer Molecular Subtypes
A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.
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Recurring Brain Tumors Evolve in Response to Microenvironment
Researchers have found that genetic evolution takes place in tumors when infiltrating gliomas recur. This evolution alters cells in a way that associates with a poor prognosis but could also lead to targeted treatments.
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New Brain-Permeable Drug Targets Melanoma Brain Metastases
Researchers have demonstrated striking preclinical efficacy of a BRAF inhibitor, C1a, that can cross the blood–brain barrier and has potent activity against melanoma metastases in the brain.
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Male Hormones Promote Sex Disparities in Bladder Cancer
Androgens – sex hormones produced in higher amounts by males – have been reported to interfere with tumor-killing CD8+ T cells, promoting sex disparities in bladder cancer.
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Study Reveals Insights Into Mitochondrial Ribosome Production
Researchers have used advanced microscopy techniques to visualize the machinery that the mitochondria use to form their proteins.
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Genes That Cause Endocrine Resistance in Breast Cancer Identified
Researchers identified 34 novel genes for further study as potential therapeutic targets for the treatment of endocrine-resistant breast cancer and triple-negative breast cancer.
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Blood Test Pinpoints Colon Cancer Patients Needing Chemotherapy
A novel blood test that assesses levels of circulating tumor DNA can identify patients who require chemo after surgery.
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