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Liquid Biopsy Could Predict Lung Cancer Immunotherapy Success Better Than a Tumor Biopsy
A protein found in extracellular vesicles shed by tumor cells could be used as a liquid biopsy biomarker to better predict the success of immunotherapy for lung cancer patients.
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Circulating DNA Shed by Colon Tumors Can Guide Chemotherapy
Measuring circulating tumor DNA following surgery to treat colon cancer can predict the risk of cancer recurrence and help direct the use of chemotherapy.
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Blocking Adenosine A2B Receptors Reduces Immunosuppression in Tumors
A team of international researchers has demonstrated that blocking adenosine A2B receptors reactivates the immune system in the tumor microenvironment and demonstrates its effectiveness in cancer immunotherapy.
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Investigational Drug Kills Rare Soft Tissue Tumor Cells
Researchers have developed a way to attack synovial sarcoma, a rare tumor of soft tissues, using an investigational drug that triggers cell death.
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Endothelial Cell Signaling May Drive Liver Cancer Progression
Researchers use lab-grown mini liver tumors co-cultured with endothelial cells, revealing chemokine signaling by these cells that drive liver cancer progression and poor survival in patients.
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Increasing Cervical Screening Interval to Five Years Is Safe With Negative HPV Test
A study of 1.3 million women has indicated that increasing the cervical screening interval from three to five years is safe for people aged 24–49, following a negative HPV test.
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Cellular Process Could Reveal Insights Into Aging-Related Diseases
A team of researchers has identified the molecular and cellular mechanisms that regulate selective autophagy in the fruit fly Drosophila melanogaster.
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Presence of T Cell Subtype in Lung Tumors Linked to Better Survival
High levels of a unique immune cell type are associated with an increased chance of remaining cancer-free after surgery for patients with non-small-cell lung cancer.
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Breast Cancer and Diabetes Join Forces To Promote Disease
Breast cancer and diabetes are both common diseases, with past epidemiological data suggesting the two are linked. A new study has identified a mechanism by which breast cancer cells could impair the function of pancreatic islet cells.
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Ultrasound-Guided Microbubbles Successfully Deliver Cancer Immunotherapy
Researchers have developed a cancer immunotherapy platform that is guided by ultrasound, generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.
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