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Targeted Drug Boosts Survival in Early-Stage Breast Cancer With Inherited BRCA Mutations
A new clinical trial demonstrates that the drug olaparib improves survival in women with high-risk, early-stage breast cancer who have inherited faults in their BRCA1 or BRCA2 genes.
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Drug Combo Effective in Patients With Recurrent ER-Positive Endometrial Cancer
A combination therapy has been shown to shrink or stabilize tumors in 75% of patients with recurrent or persistent estrogen receptor-positive endometrial cancer.
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A New Way To Detect Aggressive Cancer Cells
Researchers have designed a new way to detect the cancer stem cells that mediate metastasis, enabling the analysis of the genetic profile of individual cells.
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Younger Brain Tumor Patients Have Worse Outcomes Compared to Older Patients
Extensive data analysis of brain tumor patients aged 1 to 19 has revealed that the youngest of these patients have about half the 5-year survival rate of the oldest.
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Bone Marrow Cancer Discovery Could Help To Identify Drug Targets
Researchers have discovered that patients with an uncommon type of bone marrow cancer called ASXL1-mutant chronic myelomonocytic leukemia have distinctive epigenetic changes that can activate specific genes and cause the cancer to grow more rapidly.
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Tackling Cancer by Stabilizing Chromosomes
Researchers have discovered that the enzyme Dicer, which is found in mammalian cells, plays a key part in the structural integrity of the genome.
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CRISPR Imaging Reveals Genes Behind Tumor Immunity
A novel genetic barcoding system has been used to identify cancer cells with different gene modifications and from this, isolate the genes controlling tumor growth and response to immunotherapy.
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Enhancing the Antitumor Immune Response By Blocking Enzyme ART1
According to a study, tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments.
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Sneaking Drugs Into Cells Using a Protein-Based Microdroplet System
A team has developed a new way to deliver drugs into cells using large biological molecules, by enclosing them in a protein-based microdroplet.
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Exploiting Viral Mimicry To Treat Breast Cancer
With the help of two grants, a team of researchers is setting out to refine a cutting-edge breast cancer treatment known as viral mimicry.
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