News

Researchers have developed a new radio-labeled molecule able to selectively react with certain high-energy radicals characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time.

Researchers have discovered that a molecule known as BEND3 shuts down the expression of hundreds of genes associated with differentiation, maintaining the cell’s stem cell-like status.

The mechanism of a drug that could help treat acute myeloid leukemia has been identified. The drug activates AMPK – the main detector of cell energy levels – which triggers apoptosis.

A new project is set to launch that will use 3D cell culture to examine cell signaling pathways involved in tumorigenesis aboard the International Space Station.

A research team has used a new method called optical genome mapping to obtain more accurate information on different types of leukemia.

Results from a Phase III clinical trial indicate that adding darolutamide to other therapies can prolong the survival of men with metastatic, hormone-sensitive prostate cancer.

Researchers have designed a screening platform that will allow the testing of drugs for possible use in brain metastases.

Dr. Alice Soragni and colleagues at UCLA are using organoids to study diseases and possible treatments. In their latest study, the team developed clinically-relevant, personalized models to find therapeutics for chordoma, a rare bone cancer.

Researchers have discovered that cancer cells can weave a deactivating signal into a protective coat of armor that excludes T cells that would otherwise kill them.

A mathematical model used to describe cell signaling has been adapted to create patient-specific computer models of prostate cancer, which could help in identifying the most effective treatment for each patient.