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Normal cells usually have multiple solutions for fixing problems, for example, they have several repair mechanisms if their DNA becomes damaged. But cancer cells may "put all their eggs in one basket", leaving them vulnerable.

Researchers have discovered a way to predict which patients with ovarian cancer are resistant to platinum chemotherapy.

A new study published in Cancer Discovery uncovers a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma. The findings suggest that by targeting MCAD, it is possible to cause irreversible damage and cell death to the cancer cells

Researchers have studied the evolution of Tasmanian devils in response to a unique transmissible cancer, devil facial tumor disease.

A new study conducted by researchers from Northwestern University found that specific types of gut bacteria can protect other good bacteria from cancer treatments.

Researchers have identified a promising drug target for the treatment and prevention of aggressive, drug-resistant prostate cancer.

Researchers have shown that the calcium channel blocker (CCB), mibefradil, inhibits DNA repair independent of its CCB activity. The findings could lead to a new class of mibefradil-based DNA repair inhibitors for glioblastoma.

An in vitro study demonstrates how fungi and bacteria can activate genes linked to head and neck tumors. The researchers revealed that the metabolism of biofilms stimulates cancer cells by favoring specific cell signaling pathways associated with the development of tumors and drug resistance.

An interdisciplinary team seeks to better understand how the mechanical properties of cells operate in the body and how pathologies can disrupt these processes.

Researchers demonstrate that a membrane created from threads of a type of polymer used in vascular sutures can be loaded with drugs and implanted in the body. Once administered mechanical forces activate the polymer's electric potential triggering the slow release of the drugs.