News

Scientists at the Walter Reed Army Institute of Research demonstrated the potential of a novel blood test for cathepsin B, a well-studied protein important to brain development and function, as an indicator for a range of disease states.

Preclinical research using human tissue samples, human cell lines and mice has revealed that inositol hexaphosphate (IP6), a naturally occurring compound, inhibits medulloblastoma and can be combined with chemotherapy to kill tumor cells.

Yale researchers have used a novel mouse model of KRAS-driven lung cancer to explore what drives acquired resistance to immune checkpoint inhibitors.

An international team reports the findings of an independent assessment of five commercially available assays for tumor DNA sequencing – a fast, cheap and less invasive method to diagnose and monitor cancer.

A team of researchers has combined a wide variety of data and developed a new algorithm using machine learning technology to identify 165 previously unknown cancer genes.

Treatment with the neoantigen cancer vaccine PGV-001 following standard-of-care adjuvant therapy was well tolerated and demonstrated potential clinical benefit in patients with diverse tumor types according to a Phase 1 study. The findings were reported during the virtual AACR Annual Meeting 2021.

Preclinical research using cell lines, genetic mouse models and human pancreatic tumor tissue samples has identified the transcription factor CREB1 as a potential therapeutic target for the treatment of pancreatic cancer.

Powerful algorithms used by the likes of Netflix and Facebook can "predict" the biological language of cancer, Alzheimer's, and other neurodegenerative diseases.

It is recognized that Parkinson's disease patients are more likely to develop melanoma than the general population. Scientists now report a molecular link between the two diseases in the form of protein aggregates known as amyloids.

Researchers have shown a reduction in tumor expansion and inflammation from the inhibition of NLRP3, an intracellular complex that participates in melanoma-mediated inflammation.