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Illuminating Tumors Precisely With Novel Nanoprobes
Nanoprobes are optical probes that light up when attached to tumors. Researchers have developed a new type of nanoprobe, designed to detect cancer more accurately.
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Spherical Nucleic Acid “Drug” Triggers Death of Brain Tumor Cells
An early clinical trial in patients with glioblastoma showed an experimental spherical nucleic acid (SNA) drug, developed by Northwestern University scientists, was able to penetrate the blood–brain barrier and trigger the destruction of tumor cells.
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Using Whole Genome Sequencing To Guide Blood Cancer Treatment
A new study shows that whole genome sequencing is often more accurate than conventional genetic tests and could help determine the treatment for blood cancers such as acute myeloid leukemia and myelodysplastic syndrome.
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The Regulatory Role of Telomeres in Tumor Generation
A new study has shown that telomeres respond to external signals that induce cell proliferation, by blocking these signals it is possible to disrupt the process cancer cells exploit to become immortal.
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Getting Polygenic Risk Scores Into the Clinic
Polygenic risk scores represent a new approach for assessing a person's inherited risk for certain diseases such as Type 2 diabetes or coronary heart disease. A set of new guidelines for reporting polygenic risk scores in a consistent way, and the launch of an open database for these scores could make the data more useful in clinical care.
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Predicting Therapy Success With Individualized Models of Prostate Cancer
At present, drug response in cancer patients cannot be predicted. A research team has developed a new strategy for the generation of prostate cancer organoids that can contribute to the assessment of therapy response.
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Invasive Weed Could Help To Treat Cancer and Diabetes
An international team of scientists has discovered that extracts of a weedy grass called Andropogon virginicus appear to be effective against several human diseases, including diabetes and cancer.
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Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
The analysis of immune cells infiltrating cerebrospinal fluid enables the characterization of the tumor microenvironment in brain metastases. Findings confirm that these cells could act as novel and non-invasive biomarkers to predict patient responsiveness to immune-based therapies.
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Novel Inhibitor Shown To Combat Drug-Resistant Tumor Cells
A team of researchers from Martin Luther University Halle-Wittenberg and the University of Greifswald has developed a new inhibitor of multi-drug resistant protein 4 (MRP4). When the inhibitor was tested on drug-resistant cancer cell lines, the cancer cells began to respond to chemotherapy.
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