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How Cells Build "Mini-Muscles" Underneath Their Nucleus
Defects in the assembly of stress fibers in cells lead to multiple disorders in humans. Researchers have discovered how myosin, the motor protein responsible for the contraction of skeletal muscles, functions in non-muscle cells to build stress fibers at the inner face of the cell membrane.
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New Method Can Distinguish Cancer Stem Cells From Other Cells Based on Genetics
Cancer stem cells can replicate indefinitely, fuelling long-term cancer growth and driving relapse. Researchers have overcome the problem of cancer stem cells being difficult to isolate and study by creating a method that can be used to distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression.
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Making Personalized Cancer Therapies Effective for Multiple Patients
A new commentary in Science proposes that an emerging method of protein-based immunotherapy that works by targeting commonly occurring mutations in cancer cells, could lead to treatments that are effective for oncology patients.
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Immunotherapy is Targeted to Alterations in Tumor Suppressor Gene
Researchers have developed a novel targeted immunotherapy approach that employs new antibodies against genetically altered proteins to target cancers.
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Tissue's Microscopic Geometry Impacts Movement of Malignant Cells
New research has revealed a crucial mechanism behind the movement of malignant cells from one part of the body to another.
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CD4 T Lymphocytes Shown To Kill Cancer Cells Directly
Scientists found that when CD4 T lymphocytes were directly put in close contact with cancer cells, up to a third of them could also kill them.
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Retroviruses Cause Cancer by Rewriting the Koala Genome
An international team of scientists has shown that a retrovirus invading the koala germline explains the high frequency of koala cancer.
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64 Human Genomes Sequenced as a New Reference for Genetic Variation
Researchers have detailed the sequencing of 64 full human genomes. This will enable studies on genetic predispositions to human diseases as well as the discovery of more complex forms of genetic variation.
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Watching Nanoparticles Get in Shape
Real-time high-resolution videos have been captured by researchers showing liquid structures taking shape as nanoparticle surfactants (NPSs). The soap-like particles jam tightly together, side by side, to form a solid-like layer at the interface between oil and water.
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Metabolic Pathway for Memory T-Cell Production Mapped
Immunologists have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells. The findings have multiple implications for how the adaptive immune system responds to infections to generate such memory T cells.
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