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Team Sheds New Light on How Commonly-Used Breast Cancer Drugs Work
A class of drugs known as PARP-inhibitors used to treat hereditary breast and ovarian cancers, may not work the way we thought they did, according to new research published in Nature Communications.
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Retrogenes Are More of a Burden Than You Thought
A new study from scientists of the Max Planck Institute for Evolutionary Biology in Plön, Germany, and the Chinese Academy of Sciences in Beijing shows that the potential genetic burden of mutations arising from retrogenes is significantly greater than originally thought.
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Bioadhesive Nanoparticles Developed To Deliver Chemo Cargo Inside Tumors
Yale researchers are designing a skin cancer treatment that involves injecting nanoparticles carrying a chemotherapy agent directly into the tumor. The nanoparticles are bioadhesive, meaning they bind to the tumor and remain attached long enough to kill a significant number of the cancer cells.
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523-Gene Panel Reveals Treatment Targets for Leukemia
A gene panel that looks for approximately 10 times the number of cancer-causing genes as panels currently used to diagnose and discover treatments for a variety of cancers is effective at finding problematic genes in acute myeloid leukemia.
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Chromosome Packaging Errors May Fuel Development of B Cell-Related Blood Cancers
Errors in the way chromosomes are packed into antibody-producing B cells may play a role in the development of B cell-related blood cancers, according to a new study published in Nature Genetics.
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Potential Therapeutic Targets To Inhibit Colorectal Cancer Progression
Researchers have discovered that colorectal cancer tissues contain at least two types of fibroblasts, cancer-promoting fibroblasts and cancer-restraining fibroblasts. The balance between these two cell types is largely involved in progression of the disease.
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Optimizing Interactions Between Active Substances and Target Proteins
Scientists have investigated how the fit of potent inhibitors to their binding sites can be optimized so that they engage with their protein targets for a longer period of time.
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Team Harvests Cancer-Killing Exosomes From Natural Killer Cells
Researchers develop a microfluidic chip capable of capturing the body’s natural killer immune cells to harvest their cancer-killing exosomes.
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Encapsulating Drugs in Nanoparticles To Target Pancreatic Cancer Cells
A team of researchers has devised a novel method to deliver pancreatic cancer drugs that could make fighting the disease much easier.
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