News

In an article published in Cell Metabolism, Moffitt Cancer Center researchers report on a newly discovered biochemical pathway that protects cells from a type of cell death called ferroptosis.

Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).

A rare form of lymphoma called Waldenström macroglobulinemia (WM), currently has no known cure and only one FDA-approved treatment. Researchers have now targeted specific cell proteins that control DNA information using inhibitors, that were effective in reducing the growth of the cancer cells. When combined with a third drug the combination was even more successful at killing the WM cancer cells.

Researchers report that they have solved a long-standing question of how various types of mutations in a single gene can cause different types of disease. Their findings were published in Life Science Alliance.

Ultraviolet radiation can cause a rare type of eye cancer called conjunctival melanoma, according to research published in Nature Communications.

Researchers have created an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). This will enable scientists to identify the microbiota living in various organs in both healthy and cancerous states more accurately.

Disrupting the metabolic pathway involved in the initiation, growth and progression of melanoma could lead to the development of new treatments for melanoma, according to new research published in PLoS One.

Researchers are studying the possibility of inhibiting a protein known as low molecular weight protein tyrosine phosphatase (LMWPTP) to create novel opportunities for monitoring and treatment of cancer and other diseases.

Researchers have discovered the surprising propulsion system that enables these regenerative cells to migrate through surrounding tissue to repair damage.

A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study.