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CRISPR Gene-Editing System Destroys Cancer Cells in Animal Model
Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation.
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Blood Test Picks Out Cancers Likely To Benefit From Targeted Drugs
A simple and inexpensive blood test could pick out patients with stomach or oesophageal cancer who are likely to benefit from targeted treatment, a new study shows.
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Turning the Problem of Cancer Metastasis Into an Opportunity
A research team focused on treating cancer metastasis by delivering immune-cell-attracting chemicals into lung cancers via red blood cells.
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New Diagnostic Method Helps To Predict Which Cancer Patients Will Respond to Immunotherapy
The new predictive tool has been developed by using an advanced microscopy platform that identifies the interactions between the immune cells and the tumor cells and also provides information about the activation state of the immune checkpoints that buffer the anti-tumor response.
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New Protein Biomarker To Better Personalize Cancer Therapy
Researchers from Duke-NUS Medical School, Erasmus University Medical Center, Yale-NUS College and Duke University have found a potential way to predict who will respond to cancer therapies that block Wnt production.
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Exploring the Role of Long Non-Coding RNA in Cancer Development
Scientists at Duke-NUS Medical School have found a way to systematically investigate their functions and discovered some could play a role in pancreatic cancer.
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Key Factors Involved in Cellular Survival Identified
Sometimes cells survive after what was considered the critical step in cellular suicide. Now, scientists have identified two key factors involved in this recovery.
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Scientists Use Light To Deliver CRISPR Gene Therapy
Light-activated liposomes could help to deliver CRISPR gene therapy – and the method could prove safer and more direct than current methods.
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pH-Sensitive Iridium Complexes as Anticancer Compounds
Chemotherapy uses chemicals to reach and damage cancer cells. However, on its way towards the tumor, the drugs can affect healthy cells as well. Researchers have now presented a new family of organometallic iridium complexes that generate cytotoxicity only upon intracellular activation.
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Predicting the Risk of Severe Side Effects of Chemotherapy
The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be calculated using a new prediction model. This research may make it possible to use genetic analysis to identify cancer patients with a high probability of side effects.
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