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Leukemia often originates from the leukemic stem cell, which resides in a tumor-promoting and protecting "niche" within the bone marrow.

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA). Ideker and Brent Kuenzi, PhD, and Jisoo Park, PhD, postdoctoral researchers in his lab, describe DrugCell, a new artificial intelligence (AI) system they created that not only matches tumors to the best drug combinations, but does so in a way that makes sense to humans.

Researchers are developing and validating a novel staging system to better predict outcomes and inform treatment decisions for men diagnosed with non-metastatic prostate cancer.

As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges. One is intratumor heterogeneity -- the presence of multiple kinds of cancer cells within the same tumor. Often, these "mosaic" tumors include cells, such as polyploidal giant cancer cells, that have evolved to become aggressive and resistant to chemotherapy and radiation.

Researchers have demonstrated that a new liquid biopsy approach overcomes traditional barriers to quickly and efficiently diagnose and monitor high-grade gliomas.

A promising new biomarker that appears in patients before stomach cancer develops may help with early detection of the disease and improve patient response to therapy, according to findings in a study led by University of Arizona Health Sciences researchers.

Work by a team of researchers at Osaka University provides a breakthrough towards rapid and precise on-site diagnosis of various types of cancer and accelerates the development of innovative terahertz diagnostic devices.

Women with breast cancer, colorectal cancer, or melanoma, who were taking cholesterol-lowering medications, were less likely to die from cancer, according to a new study published in the British Journal of Clinical Pharmacology.

Twenty years after the release of the human genome, the genetic “blueprint” of human life, an international research team, including the University of British Columbia’s Chris Overall, has now mapped the first draft sequence of the human proteome.