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Precision Drug Strips Cancer of Its DNA Defenses
A new precision drug targeting cancer’s ability to repair its DNA has shown promising results in a clinical trial. The study, designed to test the drug’s safety, found that half of the participants given the new drug either alone or with platinum chemotherapy saw their cancer stop growing, and two participants saw their tumors shrink or disappear completely.
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Major Trial Assessing Breast Cancer Drug Capivasertib Begins
A major Phase 3 trial of capivasertib, a cancer drug has begun. The trial will enrol ~830 patients across 20 countries and will examine the effects of the drug in premenopausal or postmenopausal women, and men, with an advanced form of oestrogen receptor-positive, human epidermal growth factor receptor 2 negative breast cancer.
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Focused Ultrasound Shows Early Promise in Glioblastoma Brain Cancer
An innovative use of focused ultrasound is showing promise against glioblastoma and could prove useful against other difficult-to-treat cancers.
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Enigmatic Protein Sculpts DNA To Repair Harmful Damage
Scientists seeking to understand the mechanism of a DNA-repairing protein have discovered that the molecule performs its functions by first marking and then further breaking damaged DNA.
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Tumor-infiltrating Immune Cells May Play Bigger Role in Cancer Than First Thought
New research, conducted by a team from the University of California San Diego School of Medicine, indicates that the manipulation of macrophages, could be a viable treatment strategy for cancer.
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Using Organoids To Pinpoint the Right Anti-cancer Treatments for Patients
A new program named PATRIOT, is using organoids to provide a whole new level of accuracy in prescribing anti-cancer treatments to patients.
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Diagnosing and Classifying Brain Tumors Using a Blood Test
A simple but highly sensitive blood test has been shown to accurately diagnose and classify different types of brain tumor.
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Biomarker Test Is Highly Accurate at Detecting Early Kidney Cancer
Scientists have developed a novel liquid biopsy method that can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists.
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Survey Highlights the Effects of COVID-19 Pandemic on Life Scientists
Jan Korbel and Oliver Stegle, both group leaders at EMBL Heidelberg, have performed a survey of fellow life scientists in Germany, Spain, the UK, Italy, France, Canada, Turkey, and the USA to learn how the current crisis, with partial or complete institutional shutdowns, is affecting their work.
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Targeting Stem Cells Could Help To Treat Poor-prognosis Leukaemia
Researchers at Children's Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukaemia or AML.
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