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Chemo Plus Immunotherapy Shows Promise As First-line Treatment for Mesothelioma
A new combination of chemotherapy and immunotherapy shows promise for treating inoperable malignant pleural mesothelioma, according to new research.
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Cellular Stress Causes Cancer Cell Chemoresistance
A novel mechanism of chemoresistance has been identified, which is driven by the Unfolded Protein Response, a cellular stress response pathway that alters gene expression and cellular metabolism to promote adaption and cell survival upon accumulation of unfolded proteins.
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Good Vitamin D Status Can Protect Against Cancer, Review Suggests
A good vitamin D status is advantageous both in cancer prevention and in the prognosis of several cancers, according to a new research review.
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Synthesized Cell Culture Process Could Make for More Efficient Cancer Research
A team of researchers has replicated cancer cells from diseased bladder tissue in dogs, minimizing the use of costly stem cell products.
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Synthesized Fungal Molecule Reactivates Self-destruct Gene in Cancer Cells
A research team has developed a method to artificially produce a fungal compound capable of rearming the self-destruct gene in certain cancer cells, providing a potential cancer therapeutic strategy.
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New Genetic Testing Recommendations for Prostate Cancer
Key recommendations, which were published in the Journal of Clinical Oncology, include a strong endorsement to perform genetic testing of all men with metastatic prostate cancer to inform precision medicine or clinical trial eligibility.
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A New Way To Identify Genes That Drive Development of Brain Tumors
Researchers have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma – an aggressive type of brain cancer.
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Chemo Not the Only Culprit in Neuropathy – Cancer Itself Contributes Too
A new study suggests that chemotherapy might not be the only culprit in neuropathy, a neurological side effect of cancer treatment, cancer itself also contributes heavily.
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New Strategy Induces Stress Inside Tumors Causing Cancer Cell Destruction
A study describes a new strategy for tackling cancer, based on inducing potent stress in tumors, causing cell destruction by autophagy. The mechanism has been investigated using a novel antitumor drug "ABTL0812".
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New DNA Replication Insights Can Be Applied To Develop Novel Cancer Therapies
Researchers have uncovered further insights into how the replication of DNA occurs, which could be applied to help develop novel cancer treatments.
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