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Drug Shows Promise in First-in-Human Trial for Relapsed Blood Cancer

A new targeted drug may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia, showing promise in the first-in-human trials.
Cancer cells.
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Modified CAR T-Cell Therapy Shows Improved Efficacy in Preclinical Study

Researchers at the University of Freiburg have now been able to prevent the exhaustion caused by CAR-T cell therapy and thus significantly improve the effect of the therapy in a preclinical animal model.
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Tobacco Smoke Linked to Mutations That “Stop” Cancer-Fighting Proteins

A new study has revealed that tobacco smoke can cause specific DNA changes that can prevent anti-cancer proteins from being fully constructed, representing one way that tobacco smoking causes cancer.
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New Imaging Sensor Can Detect Cancer Cells

Inspired by the enhanced visual system of the Papilio xuthus butterfly, a team of researchers have developed an imaging sensor capable of “seeing” into the UV range inaccessible to human eyes.
A female clinician administers an injection to a male patient.
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Radiopharmaceutical Shows Early Promise in Prostate Cancer Trial

Researchers at Weill Cornell Medicine have led a phase 1 trial of a new drug that delivers potent radiation therapy directly and specifically to cancer cells in patients with advanced prostate cancer.
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Black Men More Likely To Have Prostate Cancer Than White Men at Same PSA Level

Black men in the United States are more likely to develop prostate cancer than white men, and after diagnosis, they’re more likely to have advanced disease and to die than white men with the disease.
A person holds a pink breast cancer ribbon.
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Potential Targets Identified for Therapy-Resistant Breast Cancers

Researchers have identified potential targets to treat therapy-resistant breast cancers, suggesting some already-approved drugs could be repurposed for certain cancer patients.
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Mechanism Behind Aspirin’s Protective Effect Against Colorectal Cancer Identified

Aspirin has been shown to reduce colorectal cancer risk and inhibit cancer progression. A new study has revealed the molecular mechanisms behind these effects.
Double helix structure of DNA.
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Researchers Identify Metabolite That Tells Cells Whether To Repair DNA

Researchers have figured out how a specific metabolite controls the activity of DNA repair and how sensitive tissues are to cancer treatment.
Cancer cells.
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Cancer Neuroscience Discovery Offers Hope for Hard-To-Treat Brain Tumors

To drive their growth, many tumors hijack nervous system signals, including those needed for brain plasticity. Stanford Medicine discoveries are opening a promising new branch of oncology research.
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