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Stem Cells in Human Embryos Commit to Specialization Surprisingly Early
The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by researchers at the Francis Crick Institute.
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Tuft Cells Found to Play a Part in Pancreatitis
Salk scientists find that specialized chemosensory cells called"tuft" cells, form during pancreatitis in mice. These findings could lead to the development of new biomarkers to test for pancreatitis and pancreatic cancer.
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Evidence for Existence of Elusive “Metabolon”
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or “metabolons,” in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers at Penn State, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular metabolites.
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Treating Cancer Drug Resistance – Study Raises Potential Red Flags
Once a patient’s tumor is resistant to one type of chemotherapy, it is more likely to be resistant to other chemotherapies as well, a situation known as multidrug resistance. For the last 35 years scientists have attempted to understand and block multidrug resistance in cancer by using experimental drugs. A new study from scientists at Scripps Research raises red flags about this strategy.
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New "Toolbox" for Urological Cancer Detection
Researchers have developed a new method for biomarker discovery of urological cancers, which enables timely diagnosis and treatment of cancer.
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Gut Microbe Bile Metabolite Boosts Immune Cells
A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells—immune cells that suppress autoimmune reactions and inflammation.
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Predicting Space Radiation Risk From Long Missions
Researchers have uncovered new clues to predicting the risks astronauts will face from space radiation on long duration missions.
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A Call for Mass COVID-19 Testing in Cancer Care
Thousands of cancer patients in the UK have had their treatment stopped or delayed because of the COVID-19 pandemic, Cancer Research UK calls for widespread testing to prevent unnecessary cancer deaths.
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Drug May Help Overcome Chemo Resistance in Ovarian Cancer
Scientists have discovered, using preclinical models, that they can overcome chemotherapy resistance in an ovarian cancer subtype by using low doses of a drug which slows cell growth.
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Caring for Cancer Patients During the COVID-19 Pandemic
The seven comprehensive cancer centres of Cancer Core Europe (CCE), have shared how they were able to rapidly reorganize their cancer healthcare systems during the COVID-19 pandemic. In this joint effort, the centers offer guidance to institutions globally by outlining the strategies they adopted to make their operations "pandemic proof".
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